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Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit

Name: Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit
Brand: SIGMA
Price: 875 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

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Synonym(s):

Anti-Aβ 42

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Size/SKU	Availability	Price
25 μg	Check Cart for Availability	$875.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD04040171

Conjugate:

unconjugated

Clone:

polyclonal

Application:

DB, ELISA (i), IHC, IP, RIA

Citations:

$875.00

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 4 kDa

species reactivity

rat, human, mouse

packaging

antibody small pack of 25 μg

technique(s)

dot blot: 0.05-1 μg/mL, immunoblotting: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: 1:200, radioimmunoassay: 1:200

UniProt accession no.

P05067

shipped in

dry ice

storage temp.

−70°C

target post-translational modification

proteolytically cleaved (Ala42)

Gene Information

human ... APP(351)
mouse ... App(11820)
rat ... App(54226)

Description

General description

Proteolytic cleavage of the amyloid precursor protein (APP) produces the small fragment amyloid β peptide. Cleavage of APP occurs mostly at residue 40 but to a lesser extent residue 42. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients.

Rabbit anti-amyloid peptide β, cleavage site 42 (Aβ42) antibody binds to human, mouse and rat Aβ42.

Immunogen

synthetic peptide of approximately 10 amino acid residues at the C-terminus of Aβ42.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Rabbit anti-Aβ42 is suitable for use in immunoblot, immunohistochemistry, immunoprecipitation, RIA, ELISA and dot blot applications.

Physical form

Solution in phosphate buffer, pH 7.4, containing approximately 25 μg of antibody.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	A8354	A3981	AB5078P
Sigma-Aldrich A1976 Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit	Sigma-Aldrich A8354 Anti-β-Amyloid antibody, Mouse monoclonal	Sigma-Aldrich A3981 Anti-β-Amyloid antibody, Mouse monoclonal	Sigma-Aldrich AB5078P Anti-Beta-Amyloid 1-42 Antibody
description affinity isolated antibody, buffered aqueous solution	description clone NAB 228, purified from hybridoma cell culture	description clone BAM-10, purified from hybridoma cell culture	description Chemicon^®, from rabbit
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 100
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form affinity purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate -
biological source rabbit	biological source mouse	biological source mouse	biological source rabbit
shipped in dry ice	shipped in dry ice	shipped in dry ice	shipped in wet ice
storage temp. −70°C	storage temp. −20°C	storage temp. −20°C	storage temp. -

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Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves

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