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AURORA A, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

AIK, ARK1, AURA, AURKA, BTAK, STK15, STK6

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Size/SKUAvailabilityPrice
10 μg
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$490.00

About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
62-84 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

$490.00


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recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

62-84 nmol/min·mg

mol wt

~72 kDa

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... AURKA(6790)

Biochem/physiol Actions

AURORA A belongs to a multigenic family of mitotic serine/threonine kinases which are involved in the control of chromosome segregation. AURORA A is involved in centrosome separation, duplication and maturation as well as in bipolar spindle assembly and stability. AURORA A is expressed and active at the highest level during G2-M phase of the cell cycle. Overexpression of AURORA A has been found to be correlated with the grade of various human solid tumours. Ectopic AURORA A overexpression in any culture cell line leads to polyploidy and centrosome amplification.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
SRP0354SAB5300336SAB5300335
description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

description

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

description

clone 4G10, ascites fluid

description

clone 1F8, ascites fluid

Gene Information

human ... AURKA(6790)

Gene Information

human ... AURKA(6790)

Gene Information

human ... AURKA(6790)

Gene Information

human ... AURKA(6790)

assay

≥70% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

-

assay

-

specific activity

62-84 nmol/min·mg

specific activity

-

specific activity

-

specific activity

-

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

-

recombinant

-

form

buffered aqueous glycerol solution

form

aqueous solution

form

-

form

-

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice


Storage Class

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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