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A2027

L-Arginine-7-amido-4-methylcoumarin hydrochloride

cathepsin H substrate

Synonym(s):

Arginine 4-methyl-7-coumarylamide

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5 mg
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€115.00
25 mg
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€392.00

About This Item

Empirical Formula (Hill Notation):
C16H21N5O3
CAS Number:
Molecular Weight:
331.37
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:

€115.00


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Quality Segment

assay

≥97% (TLC)

form

powder

solubility

acetic acid: water (1:1): 50 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@@H](N)CCCNC(N)=N)ccc12

InChI

1S/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0./s1

InChI key

PFLMUQNBZRXRHD-YDALLXLXSA-N

Application

L-Arginine-7-amido-4-methylcoumarin hydrochloride has been used as a substrate for cathepsin H from rat muscle homogenate[1] and sarcoplasmic extract.[2] It has also been used as a substrate for arginine amino-peptidase from Daphnia homogenates[3] and recombinant aminopeptidase from Toxoplasma gondii.[4]

Biochem/physiol Actions

L-Arginine-7-amido-4-methylcoumarin hydrochloride is a protease substrate.[5] It is a specific substrate for cathepsin H and not for cathepsin L and B.[6]

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This Item
C8022A4302G2761
assay

≥97% (TLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥97% (TLC)

solubility

acetic acid: water (1:1): 50 mg/mL, clear, colorless to light yellow

solubility

methanol: 20 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

solubility

water: 50 mg/mL, clear, colorless to light yellow

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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