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A2201

Amyloid β-Protein Fragment 35-25

≥95% (HPLC)

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Taglio della confezioneSKUDisponibilitàPrezzo
250 μg
Per conoscere la disponibilità, visualizza il carrello
CHF 156.00
1 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 469.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C45H81N13O14S
Numero CAS:
147740-73-6
Peso molecolare:
1060.27
NACRES:
NA.32
PubChem Substance ID:
24890634
UNSPSC Code:
51111800
MDL number:
MFCD00214225
Form:
powder
Assay:
≥95% (HPLC)

CHF 156.00

Per conoscere la disponibilità, visualizza il carrello
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Quality Level

200

assay

≥95% (HPLC)

form

powder

UniProt accession no.

P05067

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(N)CCSC)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NCC(O)=O

InChI

1S/C45H81N13O14S/c1-9-24(5)36(57-34(62)20-50-40(67)29(17-23(3)4)54-39(66)27(47)14-16-73-8)45(72)58-37(25(6)10-2)44(71)52-26(7)38(65)49-19-33(61)53-28(13-11-12-15-46)42(69)55-30(18-32(48)60)43(70)56-31(22-59)41(68)51-21-35(63)64/h23-31,36-37,59H,9-22,46-47H2,1-8H3,(H2,48,60)(H,49,65)(H,50,67)(H,51,68)(H,52,71)(H,53,61)(H,54,66)(H,55,69)(H,56,70)(H,57,62)(H,58,72)(H,63,64)

InChI key

IDGOADDOQWKZOX-UHFFFAOYSA-N

Gene Information

human ... APP(351)

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Questo articolo
A5080A2326A7973
Amyloid β-Protein Fragment 35-25 ≥95% (HPLC)

Sigma-Aldrich

A2201

Amyloid β-Protein Fragment 35-25

Amyloid β-Protein Fragment 22-35 ≥95% (HPLC)

Sigma-Aldrich

A5080

Amyloid β-Protein Fragment 22-35

Amyloid β-Protein Fragment 40-1 ≥90% (HPLC)

Sigma-Aldrich

A2326

Amyloid β-Protein Fragment 40-1

[Arg13] Amyloid-β-Protein Fragment 1-40 ≥80% (HPLC), lyophilized powder

Sigma-Aldrich

A7973

[Arg13] Amyloid-β-Protein Fragment 1-40

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥90% (HPLC)

assay

≥80% (HPLC)

form

powder

form

powder

form

powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Gene Information

human ... APP(351)

Gene Information

human ... APP(351)

Gene Information

human ... APP(351)

Gene Information

human ... APP(351)

UniProt accession no.

P05067

UniProt accession no.

P05067

UniProt accession no.

P05067

UniProt accession no.

P05067

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

Amyloid β precursor protein (APP) is a type-1 transmembrane protein.[1] APP is expressed widely and mainly found in the synapses and neurons.[2] The APP gene is mapped to human chromosome 21q21.3.[3]

Application

Amyloid β-Protein Fragment 35-25 has been used as a control peptide for Aβ-induced apoptosis to study the role of hepcidin overexpression in astrocytes against amyloid-β induced brain damage in mice.[4]

Biochem/physiol Actions

Proteolytic processing of amyloid β precursor protein (APP) forms the β amyloid protein (Aβ) as part of the brain amyloid plaques[1] which are the key biomarkers in Alzheimer′s disease. APP is known to be associated with neurogenesis, synapse formation, axonal transport, neuronal migration and neurite outgrowth. It is also related to mitochondria-associated endoplasmic reticulum membranes (MAMs) activity, antimicrobial protection, cholesterol, and iron homeostasis.[2][1] Amyloid β-Protein Fragment 35-25 is an inactive control.

Other Notes

The N—C inverted sequence of fragment 25-35

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLCC5834
SLBV2580
SLBS1693V
SLBJ6713V
071M8711

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Numero articolo commerciale globale

SKUGTIN
A2201-250UG04061833379318
A2201-1MG04061833349779

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