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A2478

APHA Compound 8

solid, ≥98% (HPLC)

Synonym(s):

3-(1-Methyl-4-phenylacetyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide

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Size/SKUAvailabilityPrice
1 mg
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$181.00

About This Item

Empirical Formula (Hill Notation):
C16H16N2O3
CAS Number:
Molecular Weight:
284.31
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

$181.00


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Product Name

APHA Compound 8, ≥98% (HPLC), solid

Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

DMSO: >10 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

Cn1cc(cc1\C=C\C(=O)NO)C(=O)Cc2ccccc2

InChI

1S/C16H16N2O3/c1-18-11-13(10-14(18)7-8-16(20)17-21)15(19)9-12-5-3-2-4-6-12/h2-8,10-11,21H,9H2,1H3,(H,17,20)/b8-7+

InChI key

UFQOXIMRSMFQRI-BQYQJAHWSA-N

Biochem/physiol Actions

HDAC (histone deacetylase) inhibitor.
One of a class of aroyl pyrrole hydroxy amide (APHA) compounds showing histone deacetylase (HDAC) inhibition, Compound 8 is the most potent and HDAC class I-selective.

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This Item
SRP0306
description

≥98% (HPLC), solid

description

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

-

form

solid

form

aqueous solution

storage temp.

2-8°C

storage temp.

−70°C

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

-


Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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