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Monoclonal Anti-Albumin antibody produced in mouse

Name: Monoclonal Anti-Albumin antibody produced in mouse
Brand: SIGMA
Price: 457 USD
Availability: InStock

clone HSA-9, ascites fluid

Synonym(s):

Anti-AFP

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Size/SKU	Availability	Price
100 μL	Available to ship TODAYfromMILWAUKEE	$457.00
0.2 mL	Available to ship TODAYfromMILWAUKEE	$591.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.46

MDL number:

MFCD00162390

Conjugate:

unconjugated

Clone:

HSA-9, monoclonal

Application:

ELISA (i)

Citations:

$457.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

HSA-9, monoclonal

contains

15 mM sodium azide

species reactivity

rhesus monkey, baboon, human

should not react with

catfish, turkey, chicken, hamster, rabbit, horse, donkey, cat, marmoset, pig, guinea pig, mouse, sheep, dog, pigeon, gibbon, bovine, goat

technique(s)

indirect ELISA: 1:500

isotype

IgG1

UniProt accession no.

P02768

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ALB(213)

Description

General description

Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin. Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease.

Monoclonal anti-Human Serum Albumin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Immunogen

Human platelets

Application

Monoclonal Anti-Albumin antibody produced in mouse has been used in:

enzyme linked immunosorbent assay (ELISA)
immunoblotting
immunofluorescence

Western blot analysis of monkey retinal protein extracts were performed using the mouse monoclonal anti-albumin antibody at 1:20000 and overnight incubation at 4 degrees. Immunohistochemistry was performed on frozen monkey retina sections with the mouse monoclonal anti-albumin antibody at 1:1000. Uptake of albumin by LLC-PK1 cells was monitored by immunofluorescence using the mouse monoclonal anti-albumin antibody. Cells were first fixed in 4% formaldehyde the incubated with the antibody for 1 hour at room temperature.

Biochem/physiol Actions

Albumin is a transport protein that binds a broad range of ligands such as fatty acids, bilirubin, hemin, drugs, amino acids and ions . Albumin may also function as a zinc carrier protein and consequently regulate physiological processes . Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease.

Serum albumins are implicated in the three major functions such as maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease.

The antibody is specific for human albumin in serum and plasma and recognizes an epitope sensitive to reduction commonly occurring in immunoblotting assays. No cross-reactivity is observed with bovine, cat, catfish, chicken, dog, donkey, gibbon, goat, guinea pig, hamster, horse, marmoset, mouse, pig, pigeon, rabbit, rat, sheep and turkey serum albumin.

Physical form

The product is provided as ascites fluid with 0.1% sodium azide as a preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	SAB4700974	SAB4200711	SAB4200688
Sigma-Aldrich A2672 Monoclonal Anti-Albumin antibody produced in mouse	Sigma-Aldrich SAB4700974 Monoclonal Anti-Albumin antibody produced in mouse	Sigma-Aldrich SAB4200711 Anti-Human Serum Albumin antibody, Mouse monoclonal	Sigma-Aldrich SAB4200688 Anti-Bovine Serum Albumin antibody, Mouse monoclonal
description clone HSA-9, ascites fluid	description clone AL-01	description clone HSA-11, purified from hybridoma cell culture	description clone BSA-33, purified from hybridoma cell culture
species reactivity rhesus monkey, baboon, human	species reactivity human	species reactivity gibbon, monkey, baboon	species reactivity sheep (highly reactive ), horse (less reactive ), dog (less reactive ), turkey (less reactive ), goat (highly reactive )
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture	antibody form purified immunoglobulin
Gene Information human ... ALB(213)	Gene Information human ... ALB(213)	Gene Information human ... ALB(213)	Gene Information dog ... Alb(403550) horse ... Alb(100034206) sheep ... Alb(443393)
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate -
clone HSA-9, monoclonal	clone AL-01, monoclonal	clone HSA-11, monoclonal	clone BSA-33, monoclonal
biological source mouse	biological source mouse	biological source mouse	biological source mouse

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Storage Class

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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