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1-Aminobenzotriazole

Name: 1-Aminobenzotriazole
Brand: SIGMA
Price: 90.8 USD
Availability: InStock

≥98% (TLC), powder, cytochrome P450 inhibitor

Sustainability features

Synonym(s):

1-Benzotriazolamine, ABT

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Size/SKU	Availability	Price
50 mg	Available to ship TODAY	$90.80
250 mg	Available to ship TODAY	$331.00

About This Item

Linear Formula:

H₂NC₆H₄N₃

CAS Number:

1614-12-6

Molecular Weight:

134.14

NACRES:

NA.77

PubChem Substance ID:

24278226

UNSPSC Code:

12352200

MDL number:

MFCD00132902

Beilstein/REAXYS Number:

607843

Assay:

≥98% (TLC)

Form:

powder

$90.80

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Properties

Product Name

1-Aminobenzotriazole,

assay

≥98% (TLC)

Quality Segment

200

form

powder

greener alternative product score

old score: 93
new score: 46
Find out more about DOZN™ Scoring

sustainability

Sustainability features

mp

81-84 °C (lit.)

solubility

ethanol: 49-51 mg/mL, clear, pale yellow to yellow

greener alternative category

SMILES string

Nn1nnc2ccccc12

InChI

1S/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H2

InChI key

JCXKHYLLVKZPKE-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives. This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Safer Solvents and Auxiliaries” and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard.

Application

1-Aminobenzotriazole has been used as a cytochrome P450 inhibitor to study the effects of estrogen on H₂O₂-induced premature senescence of vascular smooth muscle cells from old rats It has also been used to study the estrogen receptor-mediated effects of 17β-estradiol.

Biochem/physiol Actions

Suicide inhibitor of cytochrome P450 and chloroperoxidase.

1-Aminobenzotriazole (1-ABT) is used as an in vitro tool in drug discovery. It can differentiate the P450 from non-P450 enzyme systems. 1-ABT exhibits inhibitory action by covalent alteration of the heme prosthetic group in the P450 enzyme.

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This Item	N24609	916838	615870
Sigma-Aldrich A3940 1-Aminobenzotriazole	Sigma-Aldrich N24609 Nitrosobenzene	Sigma-Aldrich 916838 D-Lactic acid-1-¹³C	Sigma-Aldrich 615870 L-Phenyl-d₅-alanine
description -	description ≥97%	description ≥99 atom % ¹³C, ≥98% (CP), ≥98% (Chiral Purity)	description ≥98 atom % D, ≥99% (CP)
assay ≥98% (TLC)	assay ≥97%	assay ≥98% (Chiral Purity), ≥98% (CP)	assay 99% (CP), ≥99% (CP)
form powder	form solid	form solid	form solid
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level 200
solubility ethanol: 49-51 mg/mL, clear, pale yellow to yellow	solubility -	solubility -	solubility -
sustainability Greener Alternative Product	sustainability Greener Alternative Product	sustainability Greener Alternative Product	sustainability Greener Alternative Product
greener alternative product characteristics Waste Prevention Safer Solvents and Auxiliaries Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry.	greener alternative product characteristics Safer Solvents and Auxiliaries Design for Energy Efficiency Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry.	greener alternative product characteristics Less Hazardous Chemical Syntheses Design for Energy Efficiency Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry.	greener alternative product characteristics Less Hazardous Chemical Syntheses Safer Solvents and Auxiliaries Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry.

Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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