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A4036

Adenosine

BioReagent, suitable for cell culture

Sinonimo/i:

9-β-D-Ribofuranosyladenine, Adenine riboside, Adenine-9-β-D-ribofuranoside

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A voi/SKUDisponibilitàPrezzo
5 g
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
43,00 €
25 g
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
171,00 €

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C10H13N5O4
Numero CAS:
58-61-7
Peso molecolare:
267.24
NACRES:
NA.75
PubChem Substance ID:
24890739
eCl@ss:
32160413
UNSPSC Code:
12352207
EC Number:
200-389-9
MDL number:
MFCD00005752
Beilstein/REAXYS Number:
93029
Assay:
≥99% (HPLC)
Form:
powder

43,00 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.
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biological source

synthetic (organic)

Quality Segment

300

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

234-236 °C (lit.)

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

InChI

1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

InChI key

OIRDTQYFTABQOQ-KQYNXXCUSA-N

Gene Information

human ... ADA(100), ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), ERBB2(2064), ERBB4(2066)
rat ... Adcy2(81636), Adora1(29290), Adora2a(25369), Adora3(25370)

General description

The nucleoside adenosine consists of the purine adenine and the sugar ribose. Thus, it is also referred as adenine-D-ribose. Adenosine is an important molecule that forms nucleotides, which is a part of nucleic acids forming the DNA and RNA. The nucleotides include: adenosine monophosphate, adenosine diphosphate and adenosine triphosphate.

Application

Adenosine has been used as a supplement in DMEM (Dulbecco′s modified Eagle medium):
  • to evaluate the outgrowth of the interspecies somatic cell nucleus transfer (iSCNT)-derived blastocysts
  • to maintain the CGR8 ES (germ-line competent cell line) cells
  • for plasmid transfection and cloning of embryonic stem cells

Biochem/physiol Actions

Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
Endogenous neurotransmitter. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
Tissue injury, ischemia and abnormal cell proliferation stimulate the release of adenosine. Adenosine helps in countering the effects of reduced oxygen and energy in organs such as heart, brain and skeletal muscles mediating vasodialation. It delivers its action through G protein-coupled receptors. Adenosine also reduces the release of neurotransmitters and cellular metabolism.

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Questo articolo
A9251PHR11381012123
Adenosine BioReagent, suitable for cell culture

Sigma-Aldrich

A4036

Adenosine

Adenosine ≥99%

Sigma-Aldrich

A9251

Adenosine

Adenosine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1138

Adenosine

Adenosine United States Pharmacopeia (USP) Reference Standard

USP

1012123

Adenosine

assay

≥99% (HPLC)

assay

≥99%

assay

-

assay

-

form

powder

form

powder

form

-

form

solid

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

Gene Information

human ... ADA(100), ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), ERBB2(2064), ERBB4(2066)
rat ... Adcy2(81636), Adora1(29290), Adora2a(25369), Adora3(25370)

Gene Information

human ... ADA(100), ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), ERBB2(2064), ERBB4(2066)
rat ... Adcy2(81636), Adora1(29290), Adora2a(25369), Adora3(25370)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

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Classe di stoccaggio

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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