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A4980

Abz-FRK(Dnp)P-OH trifluoroacetate salt

≥95% (HPLC), film

Synonyme(s) :

o-Aminobenzoic acid-FRK(Dnp)P-OH, o-aminobenzoic acid-Phe-Arg-Lys(DNP)-Pro-OH trifluoroacetate salt, Abz-Phe-Arg-Lys(DNP)-Pro-OH

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A propos de cet article

Formule empirique (notation de Hill) :
C39H49N11O10 · xC2HF3O2
Poids moléculaire :
831.87 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
film
Quality level:
Service technique
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Quality Level

assay

≥95% (HPLC)

form

film

color

yellow

storage temp.

2-8°C

Application

Abz-FRK(Dnp)P-OH trifluoroacetate (TFA) is a substrate for the Angiotensin Converting Enzyme (ACE). Abz-FRK(Dnp)P-OH TFA has been used to study both the reduction of mortality of patients with sepsis and paracetamol-induced hypothermia.

Biochem/physiol Actions

Substrate for ACE (Angiotensin Converting Enzyme). Internally quenched fluorogenic substrate for Real Time Fluorescent Assay.

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

We offer many products related to angiotensin receptors for your research needs.


Jérémie Neasta et al.
British journal of pharmacology, 173(8), 1314-1328 (2016-03-31)
Using an in-house bioinformatics programme, we identified and synthesized a novel nonapeptide, H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Here, we have studied its biological activity, in vitro and in vivo, and have identified its target in the brain. The affinity of the peptide was characterized
M C Araujo et al.
Biochemistry, 39(29), 8519-8525 (2000-07-29)
Quenched fluorescence peptides were used to investigate the substrate specificity requirements for recombinant wild-type angiotensin I-converting enzyme (ACE) and two full-length mutants bearing a single functional active site (N- or C-domain). We assayed two series of bradykinin-related peptides flanked by
Arnau Hervera et al.
Molecular pain, 7, 25-25 (2011-04-14)
The local administration of μ-opioid receptor (MOR) agonists attenuates neuropathic pain but the precise mechanism implicated in this effect is not completely elucidated. We investigated if nitric oxide synthesized by neuronal (NOS1) or inducible (NOS2) nitric oxide synthases could modulate



Numéro d'article de commerce international

RéférenceGTIN
A4980-1MG04061826671016