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A5686

Arg-Gly-Glu-Ser acetate salt

≥95% (HPLC)

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2 mg

Estimated to ship onMay 13, 2026fromMILWAUKEE

$115.00
5 mg
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10 mg
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About This Item

Empirical Formula (Hill Notation):
C16H29N7O8
CAS Number:
159002-32-1
Molecular Weight:
447.44
NACRES:
NA.32
PubChem Substance ID:
329770831
UNSPSC Code:
12352202
MDL number:
MFCD00133106
Form:
powder
Assay:
≥95% (HPLC)
Biological source:
synthetic (organic)

$115.00

Estimated to ship onMay 13, 2026Details

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biological source

synthetic (organic)

Quality Level

200

assay

≥95% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

CC(O)=O.N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O

InChI

1S/C16H29N7O8.C2H4O2/c17-8(2-1-5-20-16(18)19)13(28)21-6-11(25)22-9(3-4-12(26)27)14(29)23-10(7-24)15(30)31;1-2(3)4/h8-10,24H,1-7,17H2,(H,21,28)(H,22,25)(H,23,29)(H,26,27)(H,30,31)(H4,18,19,20);1H3,(H,3,4)/t8-,9-,10-;/m0./s1

InChI key

SALKOFBHHIHLSW-PUBMXKGKSA-N

Gene Information

human ... FN1(2335)
mouse ... FN1(14268)
rat ... FN1(25661)

Application

Arg-Gly-Glu-Ser acetate salt has been used:
  • as an integrin blocking peptide to study its effects on ciliary neurotrophic factor (CNTF) regulation in astroglioma cells[1]
  • as a control peptide to study its effects on the binding of patient IgG to integrin αvβ6[2]
  • as an integrin inhibitor peptide to study its effects on cell adhesion in Capsaspora owczarzaki cells[3]

Biochem/physiol Actions

Arg-Gly-Glu-Ser peptide acts as an integrin-blocking peptide.[1]
Inhibitor of platelet aggregation

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This Item
G5779A6677A8052
Arg-Gly-Glu-Ser acetate salt ≥95% (HPLC)

Sigma-Aldrich

A5686

Arg-Gly-Glu-Ser acetate salt

Gly-Pro-Arg-Pro amide ≥97% (HPLC)

Sigma-Aldrich

G5779

Gly-Pro-Arg-Pro amide

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro ≥97% (HPLC)

Sigma-Aldrich

A6677

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro

Arg-Gly-Asp ≥97% (TLC)

Sigma-Aldrich

A8052

Arg-Gly-Asp

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic
organic)

biological source

synthetic

assay

≥95% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (TLC)

form

powder

form

-

form

powder

form

powder

Gene Information

human ... FN1(2335)
mouse ... FN1(14268)
rat ... FN1(25661)

Gene Information

human ... FN1(2335)
mouse ... FN1(14268)
rat ... FN1(25661)

Gene Information

human ... FN1(2335)

Gene Information

human ... FN1(2335)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ5343
SLCH5094
SLCC1664
SLBW8777
SLBW5172

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Helena Parra-Acero et al.
Current biology : CB, 30(21), 4270-4275 (2020-08-29)
In animals, cell-matrix adhesions are essential for cell migration, tissue organization, and differentiation, which have central roles in embryonic development [1-6]. Integrins are the major cell surface adhesion receptors mediating cell-matrix adhesion in animals. They are heterodimeric transmembrane proteins that
Seong Su Kang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(27), 9277-9287 (2012-07-06)
Ciliary neurotrophic factor (CNTF) is a potent neural cytokine with very low expression in the CNS, predominantly by astrocytes. CNTF increases rapidly and greatly following traumatic or ischemic injury. Understanding the underlying mechanisms would help to design pharmacological treatments to
Changsuk Moon et al.
Respiratory research, 10, 18-18 (2009-03-11)
Synthetic peptides containing the RGD sequence inhibit integrin-related functions in different cell systems. Here, we investigated the effects of synthetic Arg-Gly-Asp-Ser (RGDS) peptide on key inflammatory responses to intratracheal (i.t.) lipopolysaccharide (LPS) treatment and on the integrin signaled mitogen-activated protein
View All Related Papers

Global Trade Item Number

SKUGTIN
A5686-2MG04061833258392
A5686-5MG04061833258408
A5686-10MG04061833258385

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