A6185
Calpain Inhibitor I
synthetic (organic), ≥97% (TLC), cysteine protease inhibitor, powder
Synonym(s):
ALLN, Ac-LLnL-CHO, MG-101, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal, N-Acetyl-Leu-Leu-Norleu-al
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $148.00 |
25 mg | Check Cart for Availability | $556.00 |
About This Item
Product Name
Calpain Inhibitor I, ≥97% (TLC), powder
biological source
synthetic (organic)
Quality Segment
assay
≥97% (TLC)
form
powder
color
white
solubility
DMSO: soluble, ethanol: soluble
storage temp.
−20°C
SMILES string
[H]C(=O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
InChI
1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
InChI key
FMYKJLXRRQTBOR-BZSNNMDCSA-N
Gene Information
human ... CAPN1(823), CTSB(1508), PSMA1(5682)
Application
- as a component of protease inhibitor cocktail for gel shift analysis
- for treating HeLa cell cultures
- for inhibition of 26 S proteasome in 26 S proteasome inhibition assays
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥97% (TLC), powder | description InSolution, ≥95%, Inhibitor of calpain I, calpain II, cathepsin B, and cathepsin L | description Cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). | description N-Acetyl-Leu-Leu-norleucinal, synthetic |
| form powder | form solution | form solid | form powder |
| assay ≥97% (TLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay 98% (chromatographically homogeneous) |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility ethanol: soluble, DMSO: soluble | solubility - | solubility ethanol: 5 mg/mL, DMSO: 10 mg/mL | solubility ethanol: 10 mg/mL, methanol: 10 mg/mL, DMF: 10 mg/mL |
| color white | color clear colorless | color white to off-white | color - |
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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