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A6779

Adenosine 5′-triphosphate, periodate oxidized sodium salt

≥97%, bacterial (corynebacterium sp), powder

Synonym(s):

oATP, Adenosine 5′-triphosphate-2′,3′-dialdehyde

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25 mg
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$308.00
$261.80
100 mg
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$962.00

About This Item

Empirical Formula (Hill Notation):
C10H14N5O13P3
CAS Number:
71997-40-5
Molecular Weight:
505.17
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
24891137
NACRES:
NA.51
MDL number:
MFCD00056956
Assay:
≥97%
Biological source:
bacterial (corynebacterium sp)
Form:
powder
Storage temp.:
−20°C

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Product Name

Adenosine 5′-triphosphate, periodate oxidized sodium salt, ≥97%

biological source

bacterial (corynebacterium sp)

Quality Level

200

assay

≥97%

form

powder

storage temp.

−20°C

SMILES string

[Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O

InChI

1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1

InChI key

IHQATUPGVKMGLT-AUCRBCQYSA-N

General description

Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.

Application

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:
  • as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
  • as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
  • to evaluate the physiological significance of elevated intracellular ATP levels
  • increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells

Biochem/physiol Actions

Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.

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This Item
A6904A5638A9376
Adenosine 5′-triphosphate, periodate oxidized sodium salt ≥97%

Sigma-Aldrich

A6779

Adenosine 5′-triphosphate, periodate oxidized sodium salt

Adenosine 5′-diphosphate, periodate oxidized sodium salt 90-95%

Sigma-Aldrich

A6904

Adenosine 5′-diphosphate, periodate oxidized sodium salt

Adenosine 2′,5′-diphosphate sodium salt ≥95%

Sigma-Aldrich

A5638

Adenosine 2′,5′-diphosphate sodium salt

Adenosine 2′:3′-cyclic monophosphate sodium salt ≥93%

Sigma-Aldrich

A9376

Adenosine 2′:3′-cyclic monophosphate sodium salt

biological source

bacterial (corynebacterium sp)

biological source

-

biological source

-

biological source

synthetic (organic)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

solid

form

powder

form

powder

assay

≥97%

assay

90-95%

assay

≥95%

assay

≥93%

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000547593
0000547592
0000547593
0000547592
0000340211

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Searching Novel Therapeutic Targets for Scleroderma: P2X7-Receptor Is Up-regulated and Promotes a Fibrogenic Phenotype in Systemic Sclerosis Fibroblasts.
Daniela Gentile et al.
Frontiers in pharmacology, 8, 638-638 (2017-09-29)
William Foulsham et al.
Scientific reports, 9(1), 8617-8617 (2019-06-15)
Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal transplantation, we investigated the immunomodulatory mechanisms of the purinergic receptor
Ursula Schenk et al.
Science signaling, 1(39), ra6-ra6 (2008-10-02)
T cell receptor (TCR) stimulation results in the influx of Ca(2+), which is buffered by mitochondria and promotes adenosine triphosphate (ATP) synthesis. We found that ATP released from activated T cells through pannexin-1 hemichannels activated purinergic P2X receptors (P2XRs) to
View All Related Papers

Global Trade Item Number

SKUGTIN
A6779-100MG04061833258439
A6779-25MG04061833258446

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