A6779
Adenosine 5′-triphosphate, periodate oxidized sodium salt
≥97%, bacterial (corynebacterium sp), powder
Synonym(s):
oATP, Adenosine 5′-triphosphate-2′,3′-dialdehyde
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About This Item
Empirical Formula (Hill Notation):
C10H14N5O13P3
CAS Number:
Molecular Weight:
505.17
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥97%
Biological source:
bacterial (corynebacterium sp)
Form:
powder
Storage temp.:
−20°C
Product Name
Adenosine 5′-triphosphate, periodate oxidized sodium salt, ≥97%
biological source
bacterial (corynebacterium sp)
Quality Level
assay
≥97%
form
powder
storage temp.
−20°C
SMILES string
[Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O
InChI
1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1
InChI key
IHQATUPGVKMGLT-AUCRBCQYSA-N
General description
Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.
Application
Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:
- as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
- as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
- to evaluate the physiological significance of elevated intracellular ATP levels
- increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells
Biochem/physiol Actions
Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Pizarro JM, et al.
Virology, 184(2), 768-772 (1991)
Ursula Schenk et al.
Science signaling, 1(39), ra6-ra6 (2008-10-02)
T cell receptor (TCR) stimulation results in the influx of Ca(2+), which is buffered by mitochondria and promotes adenosine triphosphate (ATP) synthesis. We found that ATP released from activated T cells through pannexin-1 hemichannels activated purinergic P2X receptors (P2XRs) to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A6779-100MG | 04061833258439 |
| A6779-25MG | 04061833258446 |