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A8106

Altanserin hydrochloride hydrate

≥98% (HPLC), solid

Synonym(s):

3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride hydrate

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Size/SKUAvailabilityPrice
50 mg
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$690.00

About This Item

Empirical Formula (Hill Notation):
C22H22FN3O2S · HCl · xH2O
CAS Number:
Molecular Weight:
447.95 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$690.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

DMSO: >5 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

O.Cl.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=S)Nc4ccccc4C3=O

InChI

1S/C22H22FN3O2S.ClH.H2O/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;;/h1-8,16H,9-14H2,(H,24,29);1H;1H2

InChI key

MFGBKMPKRJCLPK-UHFFFAOYSA-N

Application

Altanserin hydrochloride hydrate has been used in the pretreatment of rat brain samples and as a non-radioactive control in the calibration curve preparation for quantifying [18F]altanserin in high-performance liquid chromatography.
Altanserin hydrochloride hydrate is a specific 5-HT2/serotonergic antagonist and has been used in a study to assess serotonin release capacity in the human brain.

Biochem/physiol Actions

The radioligand of altanserin, [18F]altanserin is useful as a positron emission tomography (PET)-radioligand for the visualization and quantification of serotonin2A (5-HT2A) receptors.
Altanserin hydrochloride hydrate is a specific 5-HT2/serotonergic antagonist.

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This Item
M2525M1875000BP252
description

≥98% (HPLC), solid

description

-

description

European Pharmacopoeia (EP) Reference Standard

description

British Pharmacopoeia (BP) Reference Standard

form

solid

form

-

form

-

form

solid

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: insoluble, DMSO: >5 mg/mL

solubility

ethanol: 5.6 mg/mL, H2O: 3.4 mg/mL

solubility

-

solubility

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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