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A8376

Acylase I aus Schweineniere

Grade II, salt-free, lyophilized powder, 300-1,500 units/mg protein

Synonym(e):

Aminoacylase, N-Acylaminosäure-Amidohydrolase

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Ihnen/SKUVerfügbarkeitPreis
1 g
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CHF 284.00

Über diesen Artikel

CAS-Nummer:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-732-3
MDL number:
EG-Nummer:
Specific activity:
300-1,500 units/mg protein

CHF 284.00


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type

Grade II

Quality Segment

form

salt-free, lyophilized powder

specific activity

300-1,500 units/mg protein

UniProt accession no.

storage temp.

−20°C

Gene Information

pig ... ACY1(396930)

Application

Acylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids .

Biochem/physiol Actions

Acylase I is a zinc metalloprotein that catalyzes the kinetic resolution of unnatural and rarely occurring α-amino acids. Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality. Acylase I catalyzes the deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. n-Butylmalonic acid is an inhibitor of acylase I. S-alkyl-N-acetyl-L-cysteines with short (C0-C3) and unbranched S-alkyl substituents have been found to be good acylase I substrates.

Analysis Note

Protein determined by biuret.

Other Notes

One unit will hydrolyze 1.0 μmole of N-acetyl-L-methionine per hr at pH 7.0 at 25 °C.

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Dieser Artikel
A3010C3755C3172
description

Grade II, salt-free, lyophilized powder, 300-1,500 units/mg protein

description

Grade I, lyophilized powder, ≥1500 units/mg protein

description

Type I, salt-free, lyophilized powder, ≥150 units/mg protein

description

lyophilized powder, 100-300 units/mg protein

specific activity

300-1,500 units/mg protein

specific activity

≥1500 units/mg protein

specific activity

≥150 units/mg protein

specific activity

100-300 units/mg protein

Gene Information

pig ... ACY1(396930)

Gene Information

pig ... ACY1(396930)

Gene Information

-

Gene Information

-

form

salt-free, lyophilized powder

form

lyophilized powder

form

salt-free, lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

UniProt accession no.

P37111

UniProt accession no.

P37111

UniProt accession no.

-

UniProt accession no.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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