Key Documents

View All Documentation

Adenine

Name: Adenine
Brand: SIGMA
Price: 82.9 CAD

≥99%, synthetic, powder

Synonym(s):

6-Aminopurine, Vitamin B₄

Select a Size

Change View

Pack Size	Availability	Price
1 g	Please contact Customer Service for Availability	$82.90
5 g	Check Cart for Availability	$99.50
25 g	Please contact Customer Service for Availability	$214.00
100 g	Please contact Customer Service for Availability	$564.00
1 kg	Please contact Customer Service for Availability	$3,580.00

About This Item

Empirical Formula (Hill Notation):

C₅H₅N₅

CAS Number:

73-24-5

Molecular Weight:

135.13

NACRES:

NA.51

PubChem Substance ID:

24891349

UNSPSC Code:

41106305

EC Number:

200-796-1

MDL number:

MFCD00041790

Beilstein/REAXYS Number:

5777

Assay:

≥99%

Biological source:

synthetic

Form:

powder

Solubility:

0.5 M HCl: soluble 20 mg/mL, Grade III, colorless to faint yellow or tan

Storage temp.:

room temp

$82.90

Please contact Customer Service for Availability

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Adenine, ≥99%

biological source

synthetic

Quality Level

200

assay

≥99%

form

powder

technique(s)

UV/Vis spectroscopy: suitable

color

white to off-white

mp

>360 °C (lit.)

solubility

0.5 M HCl: soluble 20 mg/mL, Grade III, colorless to faint yellow or tan

storage temp.

room temp

SMILES string

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

Gene Information

human ... AKT1(207), GSK3B(2932), LCK(3932), MAP3K1(4214), MAPK14(1432), MAPK8(5599), MAPK9(5601), MAPKAPK2(9261), PRKACA(5566), PRKCA(5578), RAF1(5894), ROCK2(9475)
mouse ... Mapk1(26413)
rat ... Camk2a(25400), Mapk10(25272)

Description

General description

Adenine is a purine nucleobase. It is part of DNA, and RNA. Adenine is also a component of cofactors (NAD, FAD) and signaling molecules (cAMP).

Application

Adenine is suitable for use:

as a component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boron[1]
as a food supplement for adult rats to investigate the effects of dietary adenine overload[2]
as a nucleic acid base supplement in the basal media used to grow anaerobic Bacillus mojavensis and Bacillus subtilis in a study to show that DNA or deoxyribonucleosides are required for the anaerobic growth of these bacteria[3]
as an additive to investigate the effects of adenine on CH₄ production and on fermentation by ruminal batch cultures from nonlactating Holstein cows[4]
as a part of adenine diet in rats in a study to identify blood markers for early stages of adenine-induced chronic kidney disease (CKD)[5]

Biochem/physiol Actions

Adenine is essential for many in vivo and in vitro biochemical processes. Adenine is converted to adenosine with ribose. On phosphorylation, it forms AMP, ADP and ATP. ATP is the energy currency of the cell and is required during cellular metabolism. Adenine is metabolized to is 2,8-dihydroxyadenine, which on accumulation in proximal tubules leads to the induction of chronic kidney disease (CKD) with severe anemia in rats. Adenine based derivatives elicit antiviral functionality against dsDNA viruses and are exploited for generating antiviral scaffolds.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	A2786	A5665	PHR1383
Sigma-Aldrich A8626 Adenine	Sigma-Aldrich A2786 Adenine	Sigma-Aldrich A5665 Adenine	Supelco PHR1383 Adenine
biological source synthetic	biological source synthetic	biological source -	biological source -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 300
assay ≥99%	assay ≥99%	assay ≥99%	assay -
form powder	form powder	form powder	form -
storage temp. room temp	storage temp. room temp	storage temp. -	storage temp. 2-8°C
solubility 0.5 M HCl: soluble 20 mg/mL, Grade III, colorless to faint yellow or tan	solubility 0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow	solubility 0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow	solubility -

Still not finding the right product?

Explore all of our products under Adenine

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
A8626-5G	04061833400432
A8626-25G	04061835521050
A8626-100G	04061838505200
A8626-1G	04061835511778
A8626-1KG	04061833400425

Questions

Reviews

No rating value