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Anti-Beta (β)-Amyloid antibody

Name: Anti-Beta (β)-Amyloid antibody
Brand: SIGMA
Price: 192 USD
Availability: InStock

mouse monoclonal, BAM90.1

Synonym(s):

Anti-Aβ

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Size/SKU	Availability	Price
25 μL	Check Cart for Availability	$192.00
200 μL	Estimated to ship TODAYfromMILWAUKEE	$581.00 $493.85

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD07370937

Conjugate:

unconjugated

Clone:

BAM90.1, monoclonal

Application:

EIA, IHC, IP, WB

Citations:

$192.00

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Properties

Product Name

Anti-β-Amyloid (13-28) antibody, Mouse monoclonal, clone BAM90.1, purified from hybridoma cell culture

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

BAM90.1, monoclonal

form

buffered aqueous solution

species reactivity

human

packaging

antibody small pack of 25 μL

concentration

~2 mg/mL

technique(s)

enzyme immunoassay: 0.2-0.4 μg/mL using amyloid β-protein, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1

UniProt accession no.

P05067

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... APP(351)

Description

General description

Amyloids are insoluble protein aggregates consisting of misfolded proteins and peptides. Amyloid deposition are associated with multiple neurodegenerative disorders.

The β-amyloid precursor protein (APP) is cleaved sequentially by the proteolytic enzymes β-secretase (BACE1) and γ-secretase to produce β-amyloid (Aβ) peptides with the Aβ1-42 and the Aβ1-40 forms being the most prevalent. Secreted Aβ peptides are degraded either via a re-uptake mechanism followed by endosomal degradation, or by an extracellular insulin degrading enzyme. Extracellular accumulation of Aβ leads to the formation of aggregates, fibrils and eventually amyloid deposits called neuritic plaques, which is the hallmark of Alzheimer′s disease (AD).
Monoclonal Anti β-Amyloid [13-28] recognizes the β-Amyloid peptide. The antibody epitope resides within amino acids 20-23.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Mouse Monoclonal Anti-β-Amyloid (13-28) antibody can be used for immunoblotting assays at 1:5,000. The antibody can also be used for IHC, immunoprecipitation,fluorescence infrared spectroscopy and enzyme immunoassays (02-0.4μg/ml).

Physical form

Filtered solution in 0.01 M phosphate buffered saline, pH 7.4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

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This Item	A3356	A8354	A3981
Sigma-Aldrich A8978 Anti-β-Amyloid (13-28) antibody, Mouse monoclonal	Sigma-Aldrich A3356 Anti-β-Amyloid (22-35) antibody produced in rabbit	Sigma-Aldrich A8354 Anti-β-Amyloid antibody, Mouse monoclonal	Sigma-Aldrich A3981 Anti-β-Amyloid antibody, Mouse monoclonal
description clone BAM90.1, purified from hybridoma cell culture	description affinity isolated antibody, buffered aqueous solution	description clone NAB 228, purified from hybridoma cell culture	description clone BAM-10, purified from hybridoma cell culture
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
species reactivity human	species reactivity rat, human, mouse	species reactivity human	species reactivity human
biological source mouse	biological source rabbit	biological source mouse	biological source mouse
antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin
Gene Information human ... APP(351)	Gene Information human ... APP(351) mouse ... App(11820) rat ... App(54226)	Gene Information human ... APP(351)	Gene Information human ... APP(351)
clone BAM90.1, monoclonal	clone polyclonal	clone NAB 228, monoclonal	clone BAM-10, monoclonal

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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