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A9847

Angiopoietin-2 human

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

Ang-2

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25 μg
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$1,150.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
MFCD01867019
Biological source:
human
Recombinant:
expressed in NSO cells
Assay:
>97% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
66 kDa by SDS-PAGE (reducing and non-reducing conditions), 66 kDa by SDS-PAGE
Impurities:
endotoxin, tested

$1,150.00

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biological source

human

Quality Level

200

recombinant

expressed in NSO cells

assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

66 kDa by SDS-PAGE (reducing and non-reducing conditions), 66 kDa by SDS-PAGE

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

impurities

endotoxin, tested

UniProt accession no.

O15123

storage temp.

−20°C

Gene Information

human ... ANGPT2(285)

Biochem/physiol Actions

This ligand is a naturally occurring inhibitor of angiopoietin-1 and Tie-2 both in vivo and in vitro, and has important roles in embryogenic angiogenesis and maintaining the integrity of adult vasculature.

Physical form

Lyophilized from a 0.2 μm filtered solution in 20 mM MOPS, 500 mM NaCl, 0.1% PEG-8000, 0.2% CHAPS, pH 7.0 containing 50 μg bovine serum albumin per 1 μg of cytokine.

Analysis Note

The biological activity is measured a competitive binding assay.

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Angiopoietin-2 human >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

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Sigma-Aldrich

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Sigma-Aldrich

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Insulin-Like Growth Factor Binding Protein-2 human recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ≥95% (SDS-PAGE)

Sigma-Aldrich

I5403

Insulin-Like Growth Factor Binding Protein-2 human

recombinant

expressed in NSO cells

recombinant

expressed in NSO cells

recombinant

expressed in E. coli

recombinant

expressed in NSO cells

assay

>97% (SDS-PAGE)

assay

>90% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

biological source

human

biological source

human

biological source

human

biological source

human

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

Gene Information

human ... ANGPT2(285)

Gene Information

human ... EFNA3(1944)

Gene Information

human ... CXCL13(10563)

Gene Information

human ... IGFBP2(3485)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCG5647
SLCF3192
061M1394
SLBH9267V
SLBG2825V

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Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1.
Yang, et al.
Cell Death & Disease, 14, 344-344 (2023)
B Witzenbichler et al.
The Journal of biological chemistry, 273(29), 18514-18521 (1998-07-11)
Angiopoietin-1 and its putative natural antagonist, angiopoietin-2, were recently isolated, and the critical role of angiopoietin-1 in embryogenic angiogenesis was demonstrated by targeted gene disruption. Specific biological effects of angiopoietin-1, however, have yet to be defined. In this study we
Hsiu-Mei Chen et al.
Oncotarget, 6(17), 14940-14952 (2015-04-25)
Foretinib, a multiple kinase inhibitor undergoing clinical trials, could suppress the activity of hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor-2 (VEGFR-2). In addition, Foretinib may inhibit two critical lymphangiogenic signaling receptors VEGFR-3 and TIE-2. However

Global Trade Item Number

SKUGTIN
A9847-25UG04061833412565

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