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BQ-788

≥95%, endothelin-B (ETRB) blocker, solid

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Synonym(s):

2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle, N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine sodium salt

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Size/SKUAvailabilityPrice
200 μg

Available to ship TODAYfromMILWAUKEE

$267.00

About This Item

Empirical Formula (Hill Notation):
C34H50N5NaO7
CAS Number:
Molecular Weight:
663.78
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Assay:
≥95%
Form:
solid

$267.00

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Product Name

BQ-788, ≥95%, solid

Quality Segment

assay

≥95%

form

solid

color

white

solubility

acetonitrile: 0.3 mg/mL, DMSO: 1.2 mg/mL, ethanol: 1.2 mg/mL, H2O: slightly soluble

storage temp.

−20°C

SMILES string

[Na+].CCCC[C@@H](NC(=O)[C@@H](Cc1cn(C(=O)OC)c2ccccc12)NC(=O)[C@H](CC(C)(C)C)NC(=O)N3[C@@H](C)CCC[C@H]3C)C([O-])=O

InChI

1S/C34H51N5O7.Na/c1-8-9-16-25(31(42)43)35-29(40)26(18-23-20-38(33(45)46-7)28-17-11-10-15-24(23)28)36-30(41)27(19-34(4,5)6)37-32(44)39-21(2)13-12-14-22(39)3;/h10-11,15,17,20-22,25-27H,8-9,12-14,16,18-19H2,1-7H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43);/q;+1/p-1/t21-,22+,25-,26-,27+;/m1./s1

InChI key

QCVIFBRTTLMEOV-FUKQNADPSA-M

Gene Information

human ... EDNRB(1910)
mouse ... EDNRB(13618)
rat ... EDNRB(50672)

Application

BQ-788 has been used as a selective endothelin-B (ETRB) blocker in human airway smooth muscle cells (HASMCs), uterine mesothelial cells (UtMCs)-derived vascular smooth muscle cells (VSMCs), and human umbilical vein endothelial cells (HUVECs)

Biochem/physiol Actions

Selective ETB endothelin receptor antagonist.

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This Item
E5411SML2252SML1874
description

≥95%, solid

description

from Gnomonia errabunda, ≥95% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

solid

form

-

form

powder

form

oil

assay

≥95%

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: slightly soluble, DMSO: 1.2 mg/mL, acetonitrile: 0.3 mg/mL, ethanol: 1.2 mg/mL

solubility

ethanol: 10 mg/mL, methanol: 10 mg/mL, DMSO: 10 mg/mL

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

-

color

white

color

-

color

yellow to orange

color

, colorless to dark yellow


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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