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Betacellulin human

Name: Betacellulin human
Brand: SIGMA
Price: 537.2 USD
Availability: InStock

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

BTC

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Size/SKU	Availability	Price
10 μg	Available to ship TODAYfromMILWAUKEE	$632.00 $537.20

About This Item

CAS Number:

163150-12-7

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD00676521

Biological source:

human

Recombinant:

expressed in E. coli

Assay:

≥97% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

protein 9.5 kDa

Impurities:

endotoxin, tested

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Properties

Product Name

Betacellulin human, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)

biological source

human

Quality Segment

100

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

0.1-0.6 ng/mL ED₅₀

mol wt

protein 9.5 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P35070

storage temp.

−20°C

Gene Information

human ... BTC(685)

Description

Application

This product has been used to study differentiation of pancreatic acinar cell line (AR42J) into insulin-secreting cells and has been linked to a role in the growth and differentiation of islet cells in human pancreas.

Biochem/physiol Actions

Betacellulin, and the other members of the EGF family of growth factors, binds with high affinity to both EGFR and to erbB-4. Overexpression of Betacellulin with erbB-3 and erbB-4 has been linked to human endometrial adenocarcinoma.

Preparation Note

This product was lyophilized from a 0.2 μm filtered solution of PBS containing 5 mg of bovine serum albumin. It should be reconstituted by adding sterile PBS containing 0.1% HAS or BSA to a concentration greater than 1 μg/mL.

Analysis Note

The biological activity of this product is measured by an ability to stimulate H-thmidine incorporation in EGF-responsive mouse BALB/c 3T3 fibroblasts. The EC₅₀ is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.

Disclaimer

This product should be stored at -20°C. After preparation, the product can be stored at 2-8°C for one month, or frozen in aliquots at -20°C or -70°C for more extended storage.

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This Item	B2929	S7901	T7039
Sigma-Aldrich B3670 Betacellulin human	Sigma-Aldrich B2929 B-Lymphocyte Chemoattractant human	Sigma-Aldrich S7901 Stem Cell Factor human	Sigma-Aldrich T7039 Transforming Growth Factor-β1 human
description recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)	description ≥95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture	description SCF, recombinant, expressed in E. coli, powder, suitable for cell culture	description TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
assay ≥97% (SDS-PAGE)	assay ≥95% (SDS-PAGE)	assay ≥95% (SDS-PAGE)	assay ≥95% (SDS-PAGE)
biological source human	biological source human	biological source human	biological source human
recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in CHO cells
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form powder	form powder

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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