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B3670

Betacellulin human

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

BTC

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10 μg
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$632.00
$537.20

About This Item

CAS Number:
163150-12-7
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
MFCD00676521
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥97% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
protein 9.5 kDa
Impurities:
endotoxin, tested

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Product Name

Betacellulin human, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)

biological source

human

Quality Segment

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

0.1-0.6 ng/mL ED50

mol wt

protein 9.5 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... BTC(685)

Application

This product has been used to study differentiation of pancreatic acinar cell line (AR42J) into insulin-secreting cells and has been linked to a role in the growth and differentiation of islet cells in human pancreas.

Biochem/physiol Actions

Betacellulin, and the other members of the EGF family of growth factors, binds with high affinity to both EGFR and to erbB-4. Overexpression of Betacellulin with erbB-3 and erbB-4 has been linked to human endometrial adenocarcinoma.

Preparation Note

This product was lyophilized from a 0.2 μm filtered solution of PBS containing 5 mg of bovine serum albumin. It should be reconstituted by adding sterile PBS containing 0.1% HAS or BSA to a concentration greater than 1 μg/mL.

Analysis Note

The biological activity of this product is measured by an ability to stimulate H-thmidine incorporation in EGF-responsive mouse BALB/c 3T3 fibroblasts. The EC50 is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.

Disclaimer

This product should be stored at -20°C. After preparation, the product can be stored at 2-8°C for one month, or frozen in aliquots at -20°C or -70°C for more extended storage.

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MABS458EMU180781EHU031331
Betacellulin human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)

Sigma-Aldrich

B3670

Betacellulin human

Anti-Betacellulin Antibody, clone 6G10.1 clone 6G10.1, from mouse

Sigma-Aldrich

MABS458

Anti-Betacellulin Antibody, clone 6G10.1

MISSION® esiRNA targeting mouse Btc

Sigma-Aldrich

EMU180781

MISSION® esiRNA

MISSION® esiRNA targeting human BTC

Sigma-Aldrich

EHU031331

MISSION® esiRNA

description

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)

description

clone 6G10.1, from mouse

description

targeting mouse Btc

description

targeting human BTC

assay

≥97% (SDS-PAGE)

assay

-

assay

-

assay

-

biological source

human

biological source

mouse

biological source

-

biological source

-

technique(s)

cell culture | mammalian: suitable

technique(s)

western blot: suitable, immunohistochemistry: suitable

technique(s)

-

technique(s)

-

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

lyophilized powder

form

-

form

lyophilized powder

form

lyophilized powder

Storage Class

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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