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Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse

Name: Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse
Brand: SIGMA
Price: 1334.5 CAD

clone 35928.11, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-BDNF

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Size/SKU	Availability	Price
0.5 mg	Please contact Customer Service for Availability	$1,570.00 $1,334.50

About This Item

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD01633045

Conjugate:

unconjugated

Clone:

35928.11, monoclonal

Application:

IHC (p), WB

Citations:

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Properties

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

35928.11, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 8-25 μg/mL using human spinal cord, western blot: 1-2 μg/mL

isotype

IgG1

UniProt accession no.

P23560

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BDNF(627)

Description

General description

The antibody shows ~5% cross-reactivity with recombinant human β−NGF and recombinant rat β−NGF.

Immunogen

Recombinant human BDNF, expressed in Sf 21 cells.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

Biochem/physiol Actions

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified from ascites fluid using protein A.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	AB1513	AB1513P	AB1534
Sigma-Aldrich B5050 Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse	Sigma-Aldrich AB1513 Anti-Brain Derived Neurotrophic Factor Antibody	Sigma-Aldrich AB1513P Anti-Brain Derived Neurotrophic Factor Antibody	Sigma-Aldrich AB1534 Anti-Brain Derived Neurotrophic Factor Antibody
description clone 35928.11, purified immunoglobulin, lyophilized powder	description serum, Chemicon^®	description Chemicon^®, from sheep	description serum, Chemicon^®
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form purified immunoglobulin	antibody form serum	antibody form purified immunoglobulin	antibody form serum
Gene Information human ... BDNF(627)	Gene Information human ... BDNF(627)	Gene Information human ... BDNF(627)	Gene Information human ... BDNF(627)
species reactivity human	species reactivity human, rat	species reactivity human, rat, chicken	species reactivity rat, human, mouse
clone 35928.11, monoclonal	clone polyclonal	clone polyclonal	clone polyclonal
biological source mouse	biological source sheep	biological source sheep	biological source rabbit

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c