B5150
Bacitracin zinc salt
from Bacillus licheniformis, ~70,000 U/g
Synonym(s):
Zinc bacitracin
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About This Item
biological source
Bacillus licheniformis
Quality Segment
form
powder
specific activity
~70,000 U/g
mp
250 °C (dec.) (lit.)
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC
InChI
1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1
InChI key
NKULICGUDKGGRL-FCHFGNCGSA-L
General description
Application
Biochem/physiol Actions
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description from Bacillus licheniformis, ~70,000 U/g | description Pharmaceutical Secondary Standard; Certified Reference Material | description from Bacillus licheniformis, ≥65 IU/mg | description from Bacillus colistinus |
| antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria |
| mode of action cell wall synthesis | interferes | mode of action - | mode of action cell wall synthesis | interferes | mode of action cell membrane | interferes |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form powder | form - | form powder | form powder or crystals |
| biological source Bacillus licheniformis | biological source - | biological source Bacillus licheniformis | biological source Bacillus colistinus |
| storage temp. 2-8°C | storage temp. -10 to -25°C | storage temp. 2-8°C | storage temp. 2-8°C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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