Key Documents

View All Documentation

Anti-Bak antibody produced in rabbit

Name: Anti-Bak antibody produced in rabbit
Brand: SIGMA
Price: 682.55 CAD

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-Bcl-2 Homologous Antagonist/Killer

Select a Size

Change View

Pack Size	SKU	Availability	Price
0.2 mL		Please contact Customer Service for Availability	$803.00 $682.55

About This Item

UNSPSC Code:

12352203

NACRES:

NA.46

MDL number:

MFCD00282578

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, IHC (p), WB

Citations:

$682.55

List Price$803.00Save 15%

Please contact Customer Service for Availability

A recombinant, preservative-free antibody is available for your target. Try ZRB1453

Request a Bulk Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 28 kDa

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using sections of human colon carcinoma, microarray: suitable, western blot: 1:2,000 using human epidermal carcinoma A431 whole cell extract

UniProt accession no.

Q16611

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BAK1(578)

Description

General description

Bak (Bcl-2 homologous antagonist/killer, Bak1) belongs to the B-cell lymphoma 2 (Bcl-2) family of proteins. The bak gene is mapped to chromosome 6 and encodes a 233 amino acid protein with a predicted MW of 23.4 kDa. Bak shares homology with Bcl-2 in the Bcl‐2 homology (BH) domains (BH1 and BH2). Bak is expressed in a wide variety of cell types and tissues, with the highest levels observed in heart and skeletal muscle.

Immunogen

synthetic peptide corresponding to the N-terminus of human Bak amino acids 23-38 with C-terminally added lysine, conjugated to KLH.

Application

Anti-Bak antibody produced in rabbit has been used in immunoblotting and immunohistochemistry.[1]

Biochem/physiol Actions

Bak (Bcl-2 homologous antagonist/killer, Bak1) is involved in regulating apoptosis. Bak can accelerate the rate of apoptosis when overexpressed in some cell lines. Increased Bak expression in normal and neoplastic intestinal epithelial cells results in apoptosis. However, expression of Bak in a human lymphoblastoid cell line, provided protection from apoptosis induced by serum deprivation and the oxidant menadione, suggesting that the function of Bak may be context dependent.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	HPA071231	HPA001198	SAB5700682
$Anti-Bak antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich B5897 Anti-Bak antibody produced in rabbit	Sigma-Aldrich HPA071231 Anti-RBAK antibody produced in rabbit	Sigma-Aldrich HPA001198 Anti-BTK antibody produced in rabbit	Sigma-Aldrich SAB5700682 Anti-FAK antibody produced in rabbit
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using sections of human colon carcinoma, western blot: 1:2,000 using human epidermal carcinoma A431 whole cell extract, microarray: suitable	technique(s) immunofluorescence: 0.25-2 μg/mL	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:200-1:500	technique(s) immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200, immunoprecipitation (IP): 1:50-1:100, western blot: 1:500-1:2000
form buffered aqueous solution	form buffered aqueous glycerol solution	form buffered aqueous glycerol solution	form buffered aqueous solution

Still not finding the right product?

Explore all of our products under Anti-Bak antibody produced in rabbit

— or —

Try our Product Selector Tool to narrow your options

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000436801

0000382663

0000187119

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
B5897-.2ML	04061838102515

Questions

Reviews

No rating value