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B7510

Beauvericin

≥97% (HPLC), suitable for HPLC

Synonym(s):

cyclo(D-α-Hydroxyisovaleryl-L-N-methyl-Phe)3

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Size/SKUAvailabilityPrice
5 mg
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$328.00

About This Item

Empirical Formula (Hill Notation):
C45H57N3O9
CAS Number:
26048-05-5
Molecular Weight:
783.95
UNSPSC Code:
12352209
PubChem Substance ID:
24891996
NACRES:
NA.26
MDL number:
MFCD00056846

$328.00

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Product Name

Beauvericin, ≥97% (HPLC)

Quality Segment

assay

≥97% (HPLC)

form

powder or crystals

technique(s)

HPLC: suitable

color

white to off-white

storage temp.

2-8°C

SMILES string

CC(C)C1OC(=O)C(Cc2ccccc2)N(C)C(=O)C(OC(=O)C(Cc3ccccc3)N(C)C(=O)C(OC(=O)C(Cc4ccccc4)N(C)C1=O)C(C)C)C(C)C

InChI

1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3

InChI key

GYSCAQFHASJXRS-UHFFFAOYSA-N

General description

Beauvericin is a cyclohexadepsipeptide from the fungus Beauveria bassiana that belongs to the enniatin antibiotic family. It comprises three D-hydroxyisovaleryl and N-methylphenylalanyl residues each.

Application

Beauvericin has been used as an antimicrobial bioactive compound to test its effect on engineered Saccharomyces cerevisiae strains. It has also been used as a mycotoxin standard in the reverse-phase (RP) high-pressure liquid chromatography (HPLC) to quantify mycotoxins produced by Fusarium oxysporum isolates.

Biochem/physiol Actions

Beauvericin (BEA) is a commercial entomopathogenic mycoinsecticide with antiviral, antibacterial, insecticidal, and cytotoxic properties. It elicits apoptotic and nematicidal activities as well. Beauvericin blocks multidrug efflux and Tor complex 1 (TORC1) kinase. It possesses ionophoric functionality and favors channel formation in patches of ventricular myocytes and synthetic membranes. It is shown to inhibit L-type voltage-dependent Ca2+ current in the neuroblastoma cells.
Beauvericin (BEA), a cyclohexadepsipeptide produced by the fungus Beauveria bassiana (Bals.), has antiviral, antibacterial, nematicidal, insecticidal, cytotoxic, and apoptotic activity.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
CDS00671791298
Beauvericin ≥97% (HPLC)

Sigma-Aldrich

B7510

Beauvericin

Cyclo(-Gly-Phe) AldrichCPR

Sigma-Aldrich

CDS006717

Cyclo(-Gly-Phe)

3-Hydroxyisovaleryl-L-carnitine analytical standard

Supelco

91298

3-Hydroxyisovaleryl-L-carnitine

description

≥97% (HPLC)

description

AldrichCPR

description

analytical standard

form

powder or crystals

form

solid

form

-

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

assay

≥97% (HPLC)

assay

-

assay

≥90.0% (HPLC)

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

Quality Level

200

Quality Level

-

Quality Level

100

color

white to off-white

color

-

color

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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