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Betamethasone 21-phosphate disodium

Name: Betamethasone 21-phosphate disodium
Brand: SIGMA
Price: 223 CAD

≥97%, glucocorticoid steroid, powder

Synonym(s):

Betamethasone disodium phosphate, Betamethasone sodium phosphate

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Pack Size	SKU	Availability	Price
250 mg		Please contact Customer Service for Availability	$223.00
1 g		Please contact Customer Service for Availability	$531.00 $451.35

About This Item

Empirical Formula (Hill Notation):

C₂₂H₂₈FNa₂O₈P

CAS Number:

151-73-5

Molecular Weight:

516.40

NACRES:

NA.77

PubChem Substance ID:

24892013

UNSPSC Code:

12352200

EC Number:

205-797-0

MDL number:

MFCD00200361

Assay:

≥97%

Form:

powder

Quality level:

100

$223.00

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Properties

Product Name

Betamethasone 21-phosphate disodium, ≥97%

sterility

non-sterile

Quality Level

100

assay

≥97%

form

powder

solubility

water: 50 mg/mL, clear to very slightly hazy, faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O

InChI

1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1

InChI key

PLCQGRYPOISRTQ-LWCNAHDDSA-L

Gene Information

human ... NR3C1(2908)

Description

General description

Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants

Biochem/physiol Actions

Betamethasone is used to treat neonatal respiratory distress syndrome, and psoriasis.

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1 of 1

This Item	1068004	B1045000	S5136
Sigma-Aldrich B7652 Betamethasone 21-phosphate disodium	USP 1068004 Betamethasone sodium phosphate	B1045000 Betamethasone sodium phosphate	Sigma-Aldrich S5136 Sodium phosphate dibasic
assay ≥97%	assay -	assay -	assay ≥99.0%
form powder	form -	form -	form powder or crystals
Quality Level 100	Quality Level -	Quality Level -	Quality Level 200
storage temp. room temp	storage temp. 2-8°C	storage temp. -	storage temp. room temp
solubility water: 50 mg/mL, clear to very slightly hazy, faintly yellow	solubility -	solubility -	solubility water: soluble 100 mg/mL
shipped in ambient	shipped in -	shipped in -	shipped in -

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H360FD,H373

pcodes

P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B - STOT RE 2

target_organs

Liver,Kidney,Endocrine system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Cardiovascular risk factors after antenatal exposure to betamethasone: 30-year follow-up of a randomised controlled trial

Dalziel SR, et al.

Lancet, 365(9474), 1856-1862 (2005)

Efficacy results of a 52-week, randomised, double-blind, safety study of a calcipotriol/betamethasone dipropionate two-compound product (Daivobet/Dovobet/Taclonex) in the treatment of psoriasis vulgaris

Kragballe K, et al.

Dermatology (Basel, Switzerland), 213(4), 319-326 (2006)

Preparation and characterization of a nanoparticulate formulation composed of PEG-PLA and PLA as anti-inflammatory agents.

Tsutomu Ishihara et al.

International journal of pharmaceutics, 385(1-2), 170-175 (2009-10-20)

We have prepared polymeric nanoparticles using a blend of poly(lactic acid) and monomethoxy-polyethyleneglycol(PEG)-polylactide block copolymer along with betamethasone disodium phosphate (BP). Nanoparticles have been screened for anti-inflammatory activity using experimental rat models of inflammation. In the present study, we examined

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Global Trade Item Number

SKU	GTIN
B7652-1G	04061826232422
B7652-250MG	04061838352712

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