B8279
Ro-20-1724
≥98% (HPLC), solid, cAMP phosphodiesterase inhibitor
Synonym(s):
Ro 20-1724
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Available to ship TODAYfromMILWAUKEE | $126.00 |
500 mg | Available to ship TODAYfromMILWAUKEE | $584.00 |
About This Item
Product Name
4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, solid
biological source
synthetic (organic)
Quality Segment
assay
≥98% (HPLC)
form
solid
solubility
ethanol: 7 mg/mL, H2O: insoluble
storage temp.
room temp
SMILES string
CCCCOc1cc(CC2CNC(=O)N2)ccc1OC
InChI
1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
InChI key
PDMUULPVBYQBBK-UHFFFAOYSA-N
Gene Information
human ... LITAF(9516), PDE4B(5142), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577)
rat ... Pde4a(25638)
Application
- as a cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitor to treat cells for the determination of intracellular cAMP levels
- as a component of serum-free medium
- as phosphodiesterase inhibitor in order to study the effects of protease-activated receptor-1 (PAR-1) activation on cAMP levels
Biochem/physiol Actions
Features and Benefits
1 of 1
This Item | ||
|---|---|---|
| description solid | description A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC₅₀ = 2 µM). | description powder, ReagentPlus® |
| form solid | form solid | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 |
| storage temp. room temp | storage temp. 10-30°C | storage temp. - |
| solubility H2O: insoluble, ethanol: 7 mg/mL | solubility DMSO: 20%, ethanol: 4% | solubility H2O: 15 mg/mL |
| Gene Information human ... LITAF(9516), PDE4B(5142), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577) | Gene Information - | Gene Information human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), PDE4B(5142), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577) |
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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