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B8279

Ro-20-1724

≥98% (HPLC), solid, cAMP phosphodiesterase inhibitor

Sinónimos:

Ro 20-1724

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A ustedes/SKUDisponibilidadPrecio
100 mg
Comprobar disponibilidad del carrito
MXP 2,783.00
500 mg
Comprobar disponibilidad del carrito
MXP 13,940.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C15H22N2O3
Número CAS:
Peso molecular:
278.35
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

MXP 2,783.00


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Nombre del producto

4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, solid

biological source

synthetic (organic)

Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

ethanol: 7 mg/mL, H2O: insoluble

storage temp.

room temp

SMILES string

CCCCOc1cc(CC2CNC(=O)N2)ccc1OC

InChI

1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)

InChI key

PDMUULPVBYQBBK-UHFFFAOYSA-N

Application

4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one has been used:
  • as a cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitor to treat cells for the determination of intracellular cAMP levels
  • as a component of serum-free medium
  • as phosphodiesterase inhibitor in order to study the effects of protease-activated receptor-1 (PAR-1) activation on cAMP levels

Biochem/physiol Actions

Inhibitor of cAMP phosphodiesterase. IC50 33 μM in vascular smooth muscle of the aorta.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Este artículo
B3306I0404J3770
description

solid

description

≥98% (TLC), solid

description

≥98% (HPLC), solid

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

solid

form

solid

form

solid

form

solid

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

−20°C

storage temp.

room temp

storage temp.

room temp

solubility

ethanol: 7 mg/mL, H2O: insoluble

solubility

DMSO: soluble, methanol: soluble

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

DMSO: >20 mg/mL, H2O: insoluble

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

biological source

-


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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