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Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse

Name: Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse
Brand: SIGMA
Price: 926.5 USD
Availability: InStock

clone 65529.111, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-BMP-2

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0.5 mg	Check Cart for Availability	$1,090.00 $926.50

About This Item

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD02095901

Conjugate:

unconjugated

Clone:

65529.111, monoclonal

Application:

Citations:

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Properties

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

65529.111, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

western blot: 1-2 μg/mL

isotype

IgG2b

UniProt accession no.

P12643

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BMP2(650)

Description

General description

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. Among the BMPs, BMP-2 has bone and cartilage inducing abilities. The other important functions of BMP-2 are in heart formation. BMP-2 signaling also involves active cross talk with major pathways such as Smad, MAPK, PI3K and NF-κ B.. Monoclonal Anti-BMP-2 recognizes recombinant BMP-2. It also detects BMP-4 (25% cross reactivity).

Immunogen

recombinant human BMP-2.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Monoclonal Anti-BMP-2 antibody may be used in immunoblotting at a working antibody concentration of 1-2 μg/ml.

Biochem/physiol Actions

The antibody recognizes recombinant human BMP-2. It shows approximately 25% cross-reactivity with recombinant human BMP-4.

Physical form

Lyophilizd from a 0.2 μm filtered solution in PBS, pH 7.4, with 5% trehalose.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	ZRB1489	I2136	B1814
Sigma-Aldrich B9553 Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse	Sigma-Aldrich ZRB1489 Anti-BMP-2 Antibody, clone 4O5 ZooMAb^® Rabbit Monoclonal	Sigma-Aldrich I2136 Anti-Human IgG (Fc specific) antibody produced in goat	Sigma-Aldrich B1814 Bone Morphogenetic Protein 2 human
description clone 65529.111, purified immunoglobulin, lyophilized powder	description recombinant, expressed in HEK 293 cells	description affinity isolated antibody, buffered aqueous solution	description Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
species reactivity human	species reactivity human	species reactivity -	species reactivity -
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate -
biological source mouse	biological source rabbit (recombinant)	biological source goat	biological source human
antibody form purified immunoglobulin	antibody form purified antibody	antibody form affinity isolated antibody	antibody form -
clone 65529.111, monoclonal	clone 4O5, monoclonal, recombinant monoclonal	clone polyclonal	clone -
Gene Information human ... BMP2(650)	Gene Information human ... BMP2(650)	Gene Information -	Gene Information human ... BMP2(650)

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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