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Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse

Name: Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse
Brand: SIGMA
Price: 926.5 USD
Availability: InStock

clone 65529.111, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-BMP-2

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Size/SKU	Availability	Price
0.5 mg	Available to ship TODAYfromMILWAUKEE	$1,090.00 $926.50

About This Item

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD02095901

Conjugate:

unconjugated

Clone:

65529.111, monoclonal

Application:

Citations:

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Properties

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

65529.111, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

western blot: 1-2 μg/mL

isotype

IgG2b

UniProt accession no.

P12643

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BMP2(650)

Description

General description

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. Among the BMPs, BMP-2 has bone and cartilage inducing abilities. The other important functions of BMP-2 are in heart formation. BMP-2 signaling also involves active cross talk with major pathways such as Smad, MAPK, PI3K and NF-κ B.. Monoclonal Anti-BMP-2 recognizes recombinant BMP-2. It also detects BMP-4 (25% cross reactivity).

Immunogen

recombinant human BMP-2.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Monoclonal Anti-BMP-2 antibody may be used in immunoblotting at a working antibody concentration of 1-2 μg/ml.

Biochem/physiol Actions

The antibody recognizes recombinant human BMP-2. It shows approximately 25% cross-reactivity with recombinant human BMP-4.

Physical form

Lyophilizd from a 0.2 μm filtered solution in PBS, pH 7.4, with 5% trehalose.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

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This Item	SAB1403609	B3805	MABD411
Sigma-Aldrich B9553 Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse	Sigma-Aldrich SAB1403609 Monoclonal Anti-BMP2, (C-terminal) antibody produced in mouse	Sigma-Aldrich B3805 Anti-Bone Morphogenetic Protein 5 antibody produced in goat	Sigma-Aldrich MABD411 Anti-BMP4 Antibody, clone PA354-16.1.1
description clone 65529.111, purified immunoglobulin, lyophilized powder	description clone 4B12, purified immunoglobulin, buffered aqueous solution	description affinity isolated antibody, lyophilized powder	description clone PA354-16.1.1, from mouse
clone 65529.111, monoclonal	clone 4B12, monoclonal	clone polyclonal	clone PA354-16.1.1, monoclonal
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified immunoglobulin
species reactivity human	species reactivity human	species reactivity human	species reactivity human
Gene Information human ... BMP2(650)	Gene Information human ... BMP2(650)	Gene Information human ... BMP5(653)	Gene Information human ... BMP4(652)
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source mouse	biological source goat	biological source mouse

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c