B9935
BMS-345541
≥98% (HPLC), powder
동의어(들):
N-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine hydrochloride
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
| 팩 크기/SKU | 재고 정보 | 가격 (VAT 별도) |
|---|---|---|
5 mg | 구입 가능 여부는 고객센터에 문의하십시오. | ₩382,351 |
25 mg | 구입 가능 여부는 고객센터에 문의하십시오. | ₩1,449,217 |
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C14H17N5 · HCl
CAS 번호:
Molecular Weight:
291.78
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
solubility
DMSO: 18 mg/mL, H2O: insoluble
originator
Bristol-Myers Squibb
storage temp.
2-8°C
SMILES string
Cl[H].Cc1ccc2nc(NCCN)c3ncc(C)n3c2c1
InChI
1S/C14H17N5.ClH/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15;/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18);1H
InChI key
MIDKPVLYXNLFGZ-UHFFFAOYSA-N
Application
BMS-345541 has been used:
- as an IκB kinase (IKK) complex inhibitor to study its effects on the interferon-γ (IFN-γ) production by natural killer (NK) cells[1]
- as an IKK inhibitor to study its effects on the expression of eotaxin and monocyte chemoattractant protein-1 (MCP-1) mRNA in gingival fibroblasts[2]
- as nuclear factor κB (NF-κB) pathway inhibitor to study its effects on tumor necrosis factor α (TNFα) production in human oral squamous carcinoma cells[3]
Biochem/physiol Actions
BMS-345541 is an IK B kinase (IKK) allosteric site inhibitor.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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이 품목 | |||
|---|---|---|---|
| description ≥98% (HPLC), powder | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 18 mg/mL, H2O: insoluble | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear |
| storage condition desiccated | storage condition - | storage condition desiccated | storage condition - |
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)