C0253
Chlorambucil
DNA alkylating agent, powder
Synonym(s):
4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid, 4-[Bis(2-chloroethyl)amino]benzenebutyric acid
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 g | Check Cart for Availability | $105.00 |
10 g | Check Cart for Availability | $725.00 |
About This Item
Product Name
Chlorambucil,
form
powder
Quality Segment
storage temp.
2-8°C
SMILES string
OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl
InChI
1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
InChI key
JCKYGMPEJWAADB-UHFFFAOYSA-N
Gene Information
human ... CYP2D6(1565)
Application
- as an alkylating/chemotherapeutic agent to study its anti-inflammatory effects on amyloidogenesis in mice
- as a positive control to determine the cytotoxicity in murine leukemic monocyte macrophages
- as an adenine-specific DNA-alkylating reagent in the construction of multifunctional conjugate (8950A-Chb(Cl/OH) for mutation-specific DNA alkylation in HeLa S3 cells
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description - | description British Pharmacopoeia (BP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard | description bulk package |
| form powder | form powder | form - | form powder |
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level 200 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Gene Information human ... CYP2D6(1565) | Gene Information - | Gene Information - | Gene Information human ... ALDH1A1(216), ALDH1B1(219) |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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