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C0868

Chromeceptin

≥98% (HPLC), solid

Synonym(s):

2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene, 94G6

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Size/SKUAvailabilityPrice
5 mg
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$214.00

About This Item

Empirical Formula (Hill Notation):
C19H16F3N3O
CAS Number:
Molecular Weight:
359.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$214.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

color

yellow to brown

solubility

H2O: <2 mg/mL, DMSO: >20 mg/mL

storage temp.

−20°C

SMILES string

CN(C)c1ccc2C(c3cccc(c3)C(F)(F)F)C(C#N)=C(N)Oc2c1

InChI

1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3

InChI key

GVINXTXGDDSXFQ-UHFFFAOYSA-N

Biochem/physiol Actions

Chromeceptin binds to multifunctional protein 2 (MFP-2); inhibits Insulin-like growth factor 2 (IGF2) signaling.
Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.

Features and Benefits

This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
T57703316652P1495
description

≥98% (HPLC), solid

description

96%

description

technical grade, 90%

description

1-1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

form

solid

form

-

form

liquid

form

buffered aqueous solution

assay

≥98% (HPLC)

assay

96%

assay

90%

assay

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

−20°C

solubility

H2O: <2 mg/mL, DMSO: >20 mg/mL

solubility

-

solubility

-

solubility

-

color

yellow to brown

color

-

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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