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C0979

Anti-Catalase antibody ,Mouse monoclonal

Name: Anti-Catalase antibody ,Mouse monoclonal
Brand: SIGMA
Price: 442.85 CHF
Availability: InStock

clone CAT-505, purified from hybridoma cell culture

Synonyme(s) :

Anti-CAT

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À vous/Référence	Disponibilité	Prix
0.2 mL	Disponible dès aujourd'huiDeSchnelldorf	521.00 CHF 442.85 CHF

A propos de cet article

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00802760

Conjugate:

unconjugated

Clone:

CAT-505, monoclonal

Application:

ARR, ELISA (i), ICC, IHC, WB

Citations:

442.85 CHF

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Propriétés

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

CAT-505, monoclonal

form

buffered aqueous solution

mol wt

antigen 60 kDa

species reactivity

human, mouse, bovine, rat

concentration

~2 mg/mL

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, microarray: suitable, western blot: 0.5-1 μg/mL using a whole extract of HepG2 cells

isotype

IgG1

UniProt accession no.

P04040

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CAT(847)
mouse ... Cat(12359)
rat ... Cat(24248)

Description

General description

Catalase is one of the most efficient and common enzyme found in nearly all living organisms exposed to oxygen. It is a very important enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). In most mammalian cell types catalase is localized in peroxisomes which is a tertrameric haemin-enzyme consisting of 4 identical tetrahedrally arranged subunits of 60kDa. It contains four ferriprotoporphyrin groups per molecule having a molecular mass of 240kDa.

Immunogen

human erythrocyte catalase

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (5 papers)

Monoclonal Anti-Catalase antibody produced in mouse is suitable for the following:

Immunocytochemistry
Immunohistochemistry
Indirect ELISA
Microarray
Western blotting at a concentration of 0.5-1μg/mL using whole extract of HepG2 cells
Immunofluorescence

Biochem/physiol Actions

Catalase reacts with hydrogen peroxide, a reactive oxygen species, activating its decomposition into water and molecular oxygen and it reacts with hydrogen donors. It functions as a natural anti-oxidant, protecting cells against oxidative damage of proteins, lipids and nucleic acids. Catalase also plays a role in gene expression and apoptosis. Antioxidants have been identified in association with a variety of diverse cellular functions including growth control, proliferation, differentiation, immune response, tumor promotion, apoptosis and activation of viruses.

Physical form

Solution in 0.01 M phosphate buffered saline, pH7.4, containing 15 mM sodium azide

Preparation Note

Purified from culture supernatant of hybridoma cells grown in a bioreactor.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Cet article	SAB1405562	A8481	H4538
Sigma-Aldrich C0979 Anti-Catalase antibody ,Mouse monoclonal	Sigma-Aldrich SAB1405562 Anti-CAT antibody produced in mouse	Sigma-Aldrich A8481 Anticorps anti-γ-actine monoclonal de souris antibody produced in mouse	Sigma-Aldrich H4538 Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal
species reactivity human, mouse, bovine, rat	species reactivity human	species reactivity mouse, chicken, canine, bovine, human, hamster	species reactivity rat, mouse, human
antibody form purified from hybridoma cell culture	antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture	antibody form purified from hybridoma cell culture
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone CAT-505, monoclonal	clone polyclonal	clone 2-2.1.14.17, monoclonal	clone HDAC5-35, monoclonal
biological source mouse	biological source mouse	biological source mouse	biological source mouse
Gene Information human ... CAT(847) mouse ... Cat(12359) rat ... Cat(24248)	Gene Information human ... CAT(847)	Gene Information bovine ... ACTG1(404122) chicken ... ACTG1(415296) human ... ACTG1(71) mouse ... Actg1(11465)	Gene Information human ... HDAC5(10014) mouse ... Hdac5(15184) rat ... Hdac5(84580)

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