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Anti-Cannabinoid Receptor 1 antibody produced in rabbit

Name: Anti-Cannabinoid Receptor 1 antibody produced in rabbit
Brand: SIGMA
Price: 642 USD
Availability: InStock

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-CANN6, Anti-CB-R, Anti-CB1, Anti-CB1A, Anti-CB1K5, Anti-CB1R, Anti-CNR

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Size/SKU	Availability	Price
0.1 mL	Check Cart for Availability	$642.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01633082

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ICC, WB

Citations:

$642.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen ~52 kDa

species reactivity

rat, human

concentration

1 mg/mL

technique(s)

immunocytochemistry: suitable, western blot: suitable

UniProt accession no.

P21554

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CNR1(1268)
rat ... Cnr1(25248)

Description

Immunogen

fusion protein containing amino acids 1-99 of the human CB1 receptor.

Application

Anti-Cannabinoid Receptor 1 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:250 and for immunocytochemistry at a working dilution of 1:1000.

Biochem/physiol Actions

Cannabinoids exert their well-known physiological effects through two G-protein coupled receptors, CB1 and CB2. The cannabinoid receptor type 1 (CB1) is widely distributed in mammalian tissues, with the highest concentrations found in brain neurons while CB2 receptor function primarily in the peripheral immune system, found in spleen and may be present in the central nervous system, including the retina. The cannabinoid receptor type 1 are involved in modulation of adenylate cyclase and ion channels. It is also involved in the modulation of nociception, movement, learning and memory, emotion and many other neuronal processes. It also plays an essential role in drug addiction. CB1 receptor blockade may be useful for treatment of angiotensin II-dependent hypertension and associated metabolic syndrome.

Physical form

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin, 50% glycerol, and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	C1358	SAB2502004	SAB4500345
Sigma-Aldrich C1108 Anti-Cannabinoid Receptor 1 antibody produced in rabbit	Sigma-Aldrich C1358 Anti-Cannabinoid Receptor 2 antibody produced in rabbit	Sigma-Aldrich SAB2502004 Anti-CNR1 (N-terminal) antibody produced in goat	Sigma-Aldrich SAB4500345 Anti-CNR1 antibody produced in rabbit
description affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody, buffered aqueous solution	description affinity isolated antibody
biological source rabbit	biological source rabbit	biological source goat	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
mol wt antigen ~52 kDa	mol wt -	mol wt -	mol wt antigen 52 kDa
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c