C1305
Cafestol acetate
≥98%
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| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Check Cart for Availability | $627.00 |
About This Item
Empirical Formula (Hill Notation):
C22H30O4
CAS Number:
Molecular Weight:
358.47
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
Quality Segment
assay
≥98%
form
powder
technique(s)
HPLC: suitable
color
white to off-white
storage temp.
2-8°C
SMILES string
CC(=O)OCC1(O)CC23CCC4c5ccoc5CCC4(C)C2CCC1C3
InChI
1S/C22H30O4/c1-14(23)26-13-22(24)12-21-9-5-17-16-7-10-25-18(16)6-8-20(17,2)19(21)4-3-15(22)11-21/h7,10,15,17,19,24H,3-6,8-9,11-13H2,1-2H3
InChI key
PTGGVIKFNQSFBY-UHFFFAOYSA-N
Application
Cafestol acetate has been used to determine the effects of coffee on heat shock response (HSR).
Biochem/physiol Actions
Cafestol is a coffee-specific diterpene. It has anti-carcinogenic and anti-inflammatory activities. Cafestol stimulates apoptosis in cells associated with colorectal and renal cancer (Caki cells). It is used to study mechanisms of anti-oxidation related to hydrogen peroxide induced oxidative stress and DNA damage. Cafestol increases the level of glutathione (GSH), by stimulating γ-glutamylcysteine synthetase. It acts as a chemopreventive agent by inducing cytochrome P-450.
Other Notes
Furan-containing diterpene from green coffee beans.
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This Item | |||
|---|---|---|---|
| description ≥98% | description ≥98% (HPLC) | description phyproof® Reference Substance | description phyproof® Reference Substance |
| technique(s) HPLC: suitable | technique(s) - | technique(s) - | technique(s) - |
| assay ≥98% | assay ≥98% (HPLC) | assay ≥98.0% (HPLC) | assay ≥95.0% (HPLC) |
| form powder | form powder | form - | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| color white to off-white | color white to beige | color - | color - |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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