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C1728

Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-CACH3, Anti-CACN4, Anti-CACNL1A2, Anti-CCHL1A2, Anti-Cav1.3, Anti-PASNA, Anti-SANDD

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0.2 mL
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$1,030.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02095953
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IP, WB CL
Citations:
9

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat

technique(s)

immunocytochemistry: 1:30-1:150, immunoprecipitation (IP): suitable, western blot (chemiluminescent): 1:100-1:200

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CACNA1D(776)
mouse ... Cacna1d(12289)
rat ... Cacna1d(29716)

Immunogen

synthetic peptide corresponding to amino acids 859-875 of rat α1D (Accession P27732). This epitope is highly conserved in human and hamster.

Application

Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit is suitable for the following applications:
  • immunocytochemistry at a dilution of 1:30-1:150
  • immunoprecipitation
  • western blot (chemiluminescent) at a dilution of 1:100-1:200

Biochem/physiol Actions

Cav1.3 also known as the calcium channel, voltage-dependent, L type, α1D subunit (CACNA1D), is a human gene. It responds more sensitively to depolarization than those of Cav1.2 or Cav3.1. Cav1.3 is required for proper hearing as well as sinoatrial node and brain function. It undergoes extensive alternative splicing. Alternative splicing in the C terminus and drastically modifies gating properties of the channel. The L-type calcium channel Cav1.3 is important in human glucose-induced insulin secretion and common variants in CACNA1D may contribute to type 2 diabetes.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
C5488C1603C4980
Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit affinity isolated antibody, lyophilized powder

Sigma-Aldrich

C1728

Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit

Anti-Calcium Channel (α1G Subunit) (T-type Voltage-Gated Ca2+ Channel) antibody produced in rabbit ~1 mg/mL, fractionated antiserum, buffered aqueous solution

Sigma-Aldrich

C5488

Anti-Calcium Channel (α1G Subunit) (T-type Voltage-Gated Ca2+ Channel) antibody produced in rabbit

Anti-Calcium Channel (α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

C1603

Anti-Calcium Channel (α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit

Anti-Calcium Channel (Cardiac α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit affinity isolated antibody, lyophilized powder

Sigma-Aldrich

C4980

Anti-Calcium Channel (Cardiac α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit

description

affinity isolated antibody, lyophilized powder

description

~1 mg/mL, fractionated antiserum, buffered aqueous solution

description

affinity isolated antibody

description

affinity isolated antibody, lyophilized powder

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

fractionated antiserum

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

UniProt accession no.

Q99246

UniProt accession no.

O43497

UniProt accession no.

Q13936

UniProt accession no.

P15381

form

lyophilized powder

form

buffered aqueous solution

form

-

form

lyophilized powder

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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