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C221

Carboxy-PTIO potassium salt

synthetic (organic), ≥98% (TLC), NO scavenger, powder

Sinónimos:

2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potassium salt, 2-(4-Carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-1H-imidazol-1-yloxy-3-oxide potassium salt

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A ustedes/SKUDisponibilidadPrecio
10 mg
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MXP 3,727.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C14H16KN2O4
Número CAS:
148819-94-7
Peso molecular:
315.39
UNSPSC Code:
12352200
PubChem Substance ID:
24892474
NACRES:
NA.32
MDL number:
MFCD00216153

MXP 3,727.00

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Nombre del producto

Carboxy-PTIO potassium salt,

biological source

synthetic (organic)

Quality Segment

100

assay

≥98% (TLC)

form

powder

mp

>270 °C

solubility

H2O: 100 mg/mL, DMSO: soluble (lit.)(lit.), methanol: soluble (lit.)(lit.)

storage temp.

2-8°C

SMILES string

[K+].CC1(C)N([O])C(c2ccc(cc2)C([O-])=O)=[N+]([O-])C1(C)C

InChI

1S/C14H17N2O4.K/c1-13(2)14(3,4)16(20)11(15(13)19)9-5-7-10(8-6-9)12(17)18;/h5-8H,1-4H3,(H,17,18);/q;+1/p-1

InChI key

VYEUQMVIGXFZQU-UHFFFAOYSA-M

General description

2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (carboxy-PTIO) is mainly considered as a scavenger of nitric oxide (NO).

Application

Carboxy-PTIO potassium salt has been used to check the generation of hydroxyl radicals or nitric in reaction mixtures to examine the generation of nitric oxide in reaction mixture. It has also been added to neurons to analyse its effect on glucose/oxygen/serum deprivation (GOSD) condition(4)

Biochem/physiol Actions

Carboxy-PTIO can make a quick reaction with nitric oxide (NO) to produce nitrogen dioxide (NO2). It can be used to prevent hypotension and endotoxic shock, stimulated by lipopolysaccharide in- vivo. Carboxy-PTIO can also block in vitro vascular relaxation, stimulated by NO.
Reacts with nitric oxide to form carboxy-PTI derivatives which in turn inhibits nitric oxide synthase.

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Este artículo
P4154H8759K2000
Carboxy-PTIO potassium salt

Sigma-Aldrich

C221

Carboxy-PTIO potassium salt

Polyinosinic acid potassium salt Homopolymer

Sigma-Aldrich

P4154

Polyinosinic acid potassium salt

4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt ≥98% (HPLC), powder

Sigma-Aldrich

H8759

4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt

α-Ketoglutaric acid potassium salt ≥98% (enzymatic)

Sigma-Aldrich

K2000

α-Ketoglutaric acid potassium salt

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥98% (enzymatic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

biological source

-

form

powder

form

lyophilized powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: 100 mg/mL, methanol: soluble (lit.)(lit.), DMSO: soluble (lit.)(lit.)

solubility

water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow

solubility

H2O: 50 mg/mL

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

mp

>270 °C

mp

-

mp

-

mp

-

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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