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C2562

Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse

clone C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, ascites fluid

Synonym(s):

Monoclonal Anti-Cytokeratin, pan (mixture), Panck Antibody, Panck Antibody - Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse

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Size/SKUAvailabilityPrice
100 μL

Available to ship TODAYfromMILWAUKEE

$580.00
0.2 mL

Available to ship TODAYfromMILWAUKEE

$712.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00164710
Conjugate:
unconjugated
Clone:
C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, monoclonal
Application:
IF, IHC (f), IHC (p), WB
Citations:
162

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biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, monoclonal

contains

7% horse serum and 15 mM sodium azide as preservative

species reactivity

wide range

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable using protease-digested sections of human or animal tissues, immunohistochemistry (frozen sections): suitable, indirect immunofluorescence: 1:100 using protease-digested, formalin-fixed, paraffin-embedded sections of human or animal tissues, western blot: suitable

isotype

IgG1/IgG2a

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Monoclonal Anti-Cytokeratin, pan (mouse IgG1 and IgG2a isotypes) is a mixture of monoclonal antibodies from the following clones: C-11, PCK-26, CY-90, KS1A3, M20, and A53-B/A2. Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1 (68 kDa), 4 (59 kDa), 5 (58 kDa), 8 (52 kDa), and 6 (56 kDa) are members of the type II neutral-to-basic subfamily expressed in cornified epithelia, non-cornified stratified squamous epithelia, stratified epithelia, simple epithelia and in tissues with natural or pathological turnover respectively. Cytokeratins 10 (56 kDa), 13 (54 kDa, and 18 (45 kDa) are members of the type I acidic subfamily expressed in cornified epithelia, non-cornified stratified squamous epithelia and simple epithelial cells respectively. Cytokeratin peptide 19 (40 kDa) is a type I keratin which can be expressed in both simple and in broad cells of stratifying epithelia at specific sites.

Immunogen

mixture of several monoclonal cytokeratin clones.

Application

Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse is suitable for the following applications:
  • Immunohistochemistry (formalin-fixed, paraffin-embedded sections) using protease-digested sections of human or animal tissues.
  • Immunohistochemistry (frozen sections).
  • Indirect immunofluorescence (at a working dilution of 1:100 using protease-digested, formalin-fixed, paraffin-embedded sections of human or animal tissues).
  • Immunocytochemical labeling (immunofluorescence ) of cells.
  • Western blotting.

Biochem/physiol Actions

Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in the epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.
This is a mixture of monoclonal anti-cytokeratin antibodies. It recognizes human cytokeratins 1,4,5,6,8,10,13,18, and 19. It is a broad spectrum reagent, which reacts specifically with a wide variety of normal, reactive, and neoplastic epithelial tissues. The antibody mixture reacts with simple, cornifying and non-cornifying squamous epithelia and pseudostratified epithelia. It does not react with non-epithelial normal human tissues. Increased staining intensity is seen following proteolytic treatment (protease unmasking).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
C2931C8541F0397
Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse clone C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, ascites fluid

Sigma-Aldrich

C2562

Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse

Monoclonal Anti-Cytokeratin, pan antibody produced in mouse clone C-11, ascites fluid

Sigma-Aldrich

C2931

Monoclonal Anti-Cytokeratin, pan antibody produced in mouse

Monoclonal Anti-Cytokeratin Peptide 18 antibody produced in mouse clone CY-90, ascites fluid

Sigma-Aldrich

C8541

Monoclonal Anti-Cytokeratin Peptide 18 antibody produced in mouse

Anti-Cytokeratin pan-FITC antibody, Mouse monoclonal clone PCK-26, purified from hybridoma cell culture

Sigma-Aldrich

F0397

Anti-Cytokeratin pan-FITC antibody, Mouse monoclonal

description

clone C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, ascites fluid

description

clone C-11, ascites fluid

description

clone CY-90, ascites fluid

description

clone PCK-26, purified from hybridoma cell culture

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

purified from hybridoma cell culture

clone

C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, monoclonal

clone

C-11, monoclonal

clone

CY-90, monoclonal

clone

PCK-26, monoclonal

species reactivity

wide range

species reactivity

bovine, mouse, frog, human, kangaroo rat, rat

species reactivity

wide range

species reactivity

-

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

FITC conjugate

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

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Storage Class

10 - Combustible liquids

wgk

WGK 3

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