Key Documents

Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit

Name: Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit
Brand: SIGMA
Price: 201 USD
Availability: InStock

whole antiserum

Synonym(s):

CCK Antibody - Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit, Cck Antibody

Select a Size

Change View

Size/SKU	Availability	Price
25 μL	Available to ship TODAYfromMILWAUKEE	$201.00
0.2 mL	Available to ship TODAYfromMILWAUKEE	$579.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00162230

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC (p), competitive inhibition ELISA

Citations:

$201.00

Available to ship TODAYDetails

Request a Custom Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

packaging

antibody small pack of 25 μL

technique(s)

competitive inhibition ELISA: 1:1000-1:2000, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:8,000 using indirect immunoperoxidase staining of human stomach

UniProt accession no.

P06307

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CCK(885)

Description

General description

Cholecystokinin (CCK) belongs to gastrointestinal hormone family is a neuropeptide hormone and neurotransmitter usually present in gastrointestinal (GI) tract and the central nervous system (CNS). CCK functions include enzyme secretion from pancreas, gall bladder contraction, intestinal motility; CCK will also inhibit gastrin induced acid secretion . This product is also useful for the study of mode of action, differential tissue expression and intracellular and subcellular localization of CCK in CNS and in neuroendocrine cells of digestive system. Anti-CCK-8 reacts specifically with sulfated CCK-8 and shows cross reactivity with unsulfated CCK-8 and Big Gastrin I.

Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). CCK, Big Gastrin I, and vasoactive intestinal peptide (VIP) belong to the gastrin/cholcystokinin family. hormone family. CCK has a biologically active C-terminal pentapeptide. CCK exists as a larger precursor hormone, preproCCK (114 amino acids), from which several smaller fragments are derived, sharing a C-terminal tetrapeptide and a sulfated tyrosine residue. Sulfated CCK (26-33) amide (CCK-8) is the major and the most potent CCK form in the brain and periphery. CCK is widely distributed in several brain regions, including the cerebral cortex, hippocampus, amygdala nuclei, and the hypothalamus. In the periphery, CCK is localized mainly in nerve fibers in the myenteric and submucosal ganglia, as well as in endocrine cells of the gastrointestinal tract.

Immunogen

Synthetic sulfated CCK-8 conjugated to KLH.

Application

Anti-Cholecystokinin (26-33) (CCK-8) has been used in

immunohistochemistry
double-label immunofluorescence staining
immunocytochemistry
ELISA immunoassay

Anti-cholecystokinin (26-33) (CCK-8) antibody can be used to detect CCK peptide in pancreatic cancer cells by immunocytochemistry. It may also be used for ELISA immunoassay.

Anti-cholecystokinin (26-33) (CCK-8) antibody can be used to detect CCK peptide in pancreatic cancer cells by immunocytochemistry. It may also be used for dot blot immunoassay.

Biochem/physiol Actions

Cholecystokinin (CCK) stimulates enzyme secretion from the pancreas, gall bladder contraction, and intestinal motility and it inhibits gastrin-induced acid secretion. CCK may be involved in several physiological and behavioral functions such as satiety, anxiety, memory processes, and analgesia and in disorders such as panic disorder. In the central nervous system (CNS), CCK acts as a neurotransmitter and modulates the action of other neurotransmitters such as dopamine, 5-hydroxytryptamine (5-HT), γ-Aminobutyric acid (GABA) and excitatory amino acids. The multiple biological actions of CCK are mediated by two classes of receptors, the peripheral/brain CCK-A receptors and the brain CCK-B receptors.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	SAB2100357	C8198	F7799
Sigma-Aldrich C2581 Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit	Sigma-Aldrich SAB2100357 Anti-CCK antibody produced in rabbit	Sigma-Aldrich C8198 Anti-Calcitonin Gene Related Peptide antibody produced in rabbit	$Anti-c-Fos antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich F7799 Anti-c-Fos antibody produced in rabbit
description whole antiserum	description affinity isolated antibody	description whole antiserum	description IgG fraction of antiserum, buffered aqueous solution
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form whole antiserum	antibody form affinity isolated antibody	antibody form whole antiserum	antibody form IgG fraction of antiserum
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level 200
technique(s) competitive inhibition ELISA: 1:1000-1:2000, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:8,000 using indirect immunoperoxidase staining of human stomach	technique(s) western blot: suitable	technique(s) -	technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:5,000 using human colorectal carcinoma tissue, western blot: 1:1,000 using nuclear extract of a phorbol ester-treated human A431 cells or nuclear extract of human A431 cells
shipped in dry ice	shipped in wet ice	shipped in dry ice	shipped in dry ice

Still not finding the right product?

Try our Product Selector Tool to narrow your options

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Storage Class

12 - Non Combustible Liquids

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Key Documents

Skip To

Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit

whole antiserum

Select a Size

About This Item

C2581-25UL

$201.00

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

contains

species reactivity

packaging

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Application

Biochem/physiol Actions

Disclaimer

Compare Similar Items

This Item

Still not finding the right product?

Safety Information

Flash Point (°F)

Flash Point (°C)

Storage Class

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Product Citations

Questions

Reviews

Active Filters