Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

C2581

Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit

whole antiserum

Synonym(s):

CCK Antibody - Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit, Cck Antibody

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
25 μL

Available to ship TODAYfromMILWAUKEE

$201.00
0.2 mL

Available to ship TODAYfromMILWAUKEE

$579.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00162230
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p), competitive inhibition ELISA
Citations:
56

$201.00

Available to ship TODAYDetails

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

packaging

antibody small pack of 25 μL

technique(s)

competitive inhibition ELISA: 1:1000-1:2000, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:8,000 using indirect immunoperoxidase staining of human stomach

UniProt accession no.

P06307

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CCK(885)

General description

Cholecystokinin (CCK) belongs to gastrointestinal hormone family is a neuropeptide hormone and neurotransmitter usually present in gastrointestinal (GI) tract and the central nervous system (CNS). CCK functions include enzyme secretion from pancreas, gall bladder contraction, intestinal motility; CCK will also inhibit gastrin induced acid secretion . This product is also useful for the study of mode of action, differential tissue expression and intracellular and subcellular localization of CCK in CNS and in neuroendocrine cells of digestive system. Anti-CCK-8 reacts specifically with sulfated CCK-8 and shows cross reactivity with unsulfated CCK-8 and Big Gastrin I.
Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). CCK, Big Gastrin I, and vasoactive intestinal peptide (VIP) belong to the gastrin/cholcystokinin family. hormone family. CCK has a biologically active C-terminal pentapeptide. CCK exists as a larger precursor hormone, preproCCK (114 amino acids), from which several smaller fragments are derived, sharing a C-terminal tetrapeptide and a sulfated tyrosine residue. Sulfated CCK (26-33) amide (CCK-8) is the major and the most potent CCK form in the brain and periphery. CCK is widely distributed in several brain regions, including the cerebral cortex, hippocampus, amygdala nuclei, and the hypothalamus. In the periphery, CCK is localized mainly in nerve fibers in the myenteric and submucosal ganglia, as well as in endocrine cells of the gastrointestinal tract.

Immunogen

Synthetic sulfated CCK-8 conjugated to KLH.

Application

Anti-Cholecystokinin (26-33) (CCK-8) has been used in

  • immunohistochemistry
  • double-label immunofluorescence staining
  • immunocytochemistry
  • ELISA immunoassay
Anti-cholecystokinin (26-33) (CCK-8) antibody can be used to detect CCK peptide in pancreatic cancer cells by immunocytochemistry. It may also be used for ELISA immunoassay.
Anti-cholecystokinin (26-33) (CCK-8) antibody can be used to detect CCK peptide in pancreatic cancer cells by immunocytochemistry. It may also be used for dot blot immunoassay.

Biochem/physiol Actions

Cholecystokinin (CCK) stimulates enzyme secretion from the pancreas, gall bladder contraction, and intestinal motility and it inhibits gastrin-induced acid secretion. CCK may be involved in several physiological and behavioral functions such as satiety, anxiety, memory processes, and analgesia and in disorders such as panic disorder. In the central nervous system (CNS), CCK acts as a neurotransmitter and modulates the action of other neurotransmitters such as dopamine, 5-hydroxytryptamine (5-HT), γ-Aminobutyric acid (GABA) and excitatory amino acids. The multiple biological actions of CCK are mediated by two classes of receptors, the peripheral/brain CCK-A receptors and the brain CCK-B receptors.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
C8198C5348M8440
Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit whole antiserum

Sigma-Aldrich

C2581

Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit

Anti-Calcitonin Gene Related Peptide antibody produced in rabbit whole antiserum

Sigma-Aldrich

C8198

Anti-Calcitonin Gene Related Peptide antibody produced in rabbit

Anti-Corticotropin Releasing Factor antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

C5348

Anti-Corticotropin Releasing Factor antibody produced in rabbit

Anti-MCH antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

M8440

Anti-MCH antibody produced in rabbit

description

whole antiserum

description

whole antiserum

description

IgG fraction of antiserum, buffered aqueous solution

description

IgG fraction of antiserum, buffered aqueous solution

antibody form

whole antiserum

antibody form

whole antiserum

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

species reactivity

human

species reactivity

rat

species reactivity

frog, canine, sheep, rat, human, mouse, pig, bovine

species reactivity

human

Still not finding the right product?

Try our Product Selector Tool to narrow your options

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters