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C3545

Monoclonal Anti-Calmodulin antibody produced in mouse

clone 6D4, ascites fluid

Synonym(s):

Anti-CALM3, Anti-calmodulin

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0.2 mL

Available to ship TODAYfromMILWAUKEE

$449.00
$381.65

About This Item

UNSPSC Code:
12352203
NACRES:
NA.44
MDL number:
MFCD00162206
Conjugate:
unconjugated
Clone:
6D4, monoclonal
Application:
WB
Citations:
13

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biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

6D4, monoclonal

contains

15 mM sodium azide as preservative

species reactivity

chicken, Dictyostelium discoideum, bovine, rat

technique(s)

western blot: 1:2,000 using a bovine brain calmodulin preparation

isotype

IgG1

UniProt accession no.

P0DP29

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Calm1(24242)

General description

Calmodulin belongs to a family of structurally homologous Ca2+-binding proteins. CALM1 gene is located on human chromosome 14q32.11.
Calmodulin is a highly conserved 17kDa calcium binding protein found in all eukaryotic cells. It is a multifunctional molecule. Monoclonal anti-Calmodulin (mouse IgG1 isotype) is derived from the 6D4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with calmodulin, purified from Dictyostelium discoideum and conjugated to KLH.

Immunogen

preparation of purified calmodulin from Dictyostelium discoideum conjugated to KLH.

Application

Monoclonal Anti-Calmodulin antibody produced in mouse has been used in:
  • enzyme-linked immunosorbent assay (ELISA)
  • immunoblot
  • dot blot
  • immunocytochemistry
  • immunoprecipitation
  • immunofluorescence[1]

Biochem/physiol Actions

Calmodulin is a ubiquitous molecule which can bind up to 4 calcium ions, regulating and mediating a wide variety of biochemical processes.
The antibody recognizes native and SDS-denatured calmodulin.
These antibodies are directed against different epitopes within the calmodulin molecule.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
C9848C6344SAB4301475
Monoclonal Anti-Calmodulin antibody produced in mouse clone 6D4, ascites fluid

Sigma-Aldrich

C3545

Monoclonal Anti-Calmodulin antibody produced in mouse

Monoclonal Anti-Calbindin-D-28K antibody produced in mouse clone CB-955, ascites fluid

Sigma-Aldrich

C9848

Monoclonal Anti-Calbindin-D-28K antibody produced in mouse

Monoclonal Anti-Connexin-32 antibody produced in mouse clone CXN-32, ascites fluid, buffered aqueous solution

Sigma-Aldrich

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Monoclonal Anti-Connexin-32 antibody produced in mouse

Anti-phospho-Calmodulin (pThr79/Ser81) antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4301475

Anti-phospho-Calmodulin (pThr79/Ser81) antibody produced in rabbit

Gene Information

rat ... Calm1(24242)

Gene Information

human ... CALB1(793)
mouse ... Calb1(12307)
rat ... Calb1(83839)

Gene Information

human ... GJB1(2705), GJB2(2706)
mouse ... Gjb1(14618)
rat ... Gja1(24392), Gjb1(29584)

Gene Information

human ... CALM3(808)

species reactivity

chicken, Dictyostelium discoideum, bovine, rat

species reactivity

mouse, human, guinea pig, canine, sheep, rat, pig, rabbit, feline, bovine, goat

species reactivity

human, rat, mouse

species reactivity

rat, mouse, human

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rabbit

clone

6D4, monoclonal

clone

CB-955, monoclonal

clone

CXN-32, monoclonal

clone

polyclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

affinity isolated antibody

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000193766
0000179090
0000179090
0000193766
019M4880V

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Association between the polymorphisms of CALM1 gene and osteoarthritis risk: a meta-analysis based on observational studies
Yang H, et al.
Bioscience Reports, 38(5), BSR20181128-BSR20181128 (2018)
H C Lee et al.
The Journal of biological chemistry, 270(16), 9060-9066 (1995-04-21)
Cyclic ADP-ribose (cADPR) is emerging as an endogenous regulator of Ca2+-induced Ca2+ release (CICR), and we have recently demonstrated that its action is mediated by calmodulin (CaM) (Lee, H. C., Aarhus, R., Graeff, R., Gurnack, M. E., and Walseth, T.
The role of calmodulin and related proteins in plant cell function: an ever-thickening plot
Bergey DR, et al.
Springer Science Reviews, 2(1-2), 145-159 (2014)
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Global Trade Item Number

SKUGTIN
C3545-.2ML04061838104281

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