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Anti-Connexin-32 (106-124) antibody produced in rabbit

Name: Anti-Connexin-32 (106-124) antibody produced in rabbit
Brand: SIGMA
Price: 854 CAD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CMTX, Anti-CMTX1, Anti-CX32

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Pack Size	SKU	Availability	Price
0.2 mL		Please contact Customer Service for Availability	$854.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01633266

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC (f), WB

Citations:

$854.00

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Properties

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 27 kDa

species reactivity

mouse, human, rat

technique(s)

immunohistochemistry (frozen sections): 1:400 using frozen rat liver sections, western blot: 1:400 using a rat liver membrane preparation

UniProt accession no.

P08034

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GJB1(2705)
mouse ... Gjb1(14618)
rat ... Gjb1(29584)

Description

General description

Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kDa. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. The 27kD connexin protein (connexin 32, Cx32) is expressed in several tissues.

Immunogen

synthetic human connexin-32 peptide (amino acids 106-124).

Application

Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable for immunohistochemistry (frozen sections) at a dilution of 1:400 using frozen rat liver tissue. It is also suitable for western blot at a dilution of 1:400 using a rat liver membrane preparation.

Anti-Connexin-32 (106-124) antibody produced in rabbit has been used in:

western blotting
immunofluorescence
immunohistology

Biochem/physiol Actions

Cx32 mutations is associated with X-linked Charcot-Marie-Tooth (CMTX) disease, which leads to myelin disruption and axonal degeneration.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	C6344	C6219	SAB4200730
Sigma-Aldrich C3595 Anti-Connexin-32 (106-124) antibody produced in rabbit	Sigma-Aldrich C6344 Monoclonal Anti-Connexin-32 antibody produced in mouse	Sigma-Aldrich C6219 Anti-Connexin-43 antibody produced in rabbit	Sigma-Aldrich SAB4200730 Anti-Connexin 43 antibody, Mouse monoclonal
biological source rabbit	biological source mouse	biological source rabbit	biological source mouse
antibody form affinity isolated antibody	antibody form ascites fluid	antibody form affinity isolated antibody	antibody form culture supernatant
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
UniProt accession no. P08034	UniProt accession no. P08034	UniProt accession no. P17302	UniProt accession no. P17302
clone polyclonal	clone CXN-32, monoclonal	clone polyclonal	clone CXN-6, monoclonal

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection

Rodriguez-Sinovas A, et al.

The Journal of Physiology, 588(7), 1139-1151 (2010)

The expression of mesenchymal, neural and haematopoietic stem cell markers in adult hepatocytes proliferating in vitro

Koenig S, et al.

Journal of Hepatology, 44(6), 1115-1124 (2006)

Transient, recurrent, white matter lesions in X-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation

Hanemann CO, et al.

Archives of Neurology, 60(4), 605-609 (2003)

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Global Trade Item Number

SKU	GTIN
C3595-.2ML	04061837873157

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