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C3678

Anti-Pan Cadherin antibody produced in rabbit

whole antiserum

Synonym(s):

Anti-ACOGS, Anti-ARVD14, Anti-CD325, Anti-CDHN, Anti-CDw325, Anti-NCAD

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0.2 mL
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$589.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00162729
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p), WB
Citations:
55

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

mol wt

antigen 135 kDa

contains

15 mM sodium azide

species reactivity

rabbit, cat, chicken, human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using protease-digested animal heart sections, indirect immunofluorescence: 1:100 using cultured MDBK cells, western blot: 1:200

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

chicken ... CDH2(414745)

General description

Cadherins are glycoprotein receptors that regulate Ca2+-dependant adhesion in cells. Cadherins are associated with adherens junctions and are mainly involved in morphogenesis of cells and tissues. P-cadherin is expressed in epithelial cells and its over-expression has been associated with breast cancer metastasis and invasion . Anti-Pan Cadherin antibody is specific for cadherins in a wide range of organisms including chickens, rabbits and rats.

Immunogen

Synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue (24 amino acids) coupled with glutaraldehyde to keyhole limpet hemocyanin (KLH).

Application

Anti-Pan Cadherin antibody is suitable for use in confocal immunofluorescence using rat ventricular myocytes and western blot (1:200). The antibody may also be used for indirect immunofluorescence (1:100 using cultured MDBK cells) and immunohistochemistry (in formalin-fixed, paraffin-embedded sections or at 1:1,000 dilutions using protease-digested animal heart sections). Additionally, the product can be used in indirect immunoblot (135 kDa band in chicken or rabbit heart extracts), immunoperoxidase and immunoelectron-microscopy assays.
May be used for the detection of members of the cadherin family or genetically engineered proteins containing the C-terminal cadherin tail, and for demonstration of adherens type cell-cell junctions regardless of their cadherin type.

Biochem/physiol Actions

The epitope recognized by the antibody is shared by a wide variety of organisms.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Pan Cadherin antibody produced in rabbit whole antiserum

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Sigma-Aldrich

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Monoclonal Anti-N-Cadherin antibody produced in mouse

Anti-N-Cadherin antibody, Mouse monoclonal clone GC-4, purified from hybridoma cell culture

Sigma-Aldrich

C3865

Anti-N-Cadherin antibody, Mouse monoclonal

description

whole antiserum

description

clone CH-19, ascites fluid

description

clone GC-4, ascites fluid

description

clone GC-4, purified from hybridoma cell culture

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

whole antiserum

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

purified immunoglobulin

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

UniProt accession no.

P19022

UniProt accession no.

P12830

UniProt accession no.

P19022

UniProt accession no.

P19022

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Storage Class

12 - Non Combustible Liquids

WGK

nwg

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