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C4915

S-(+)-Chlorpheniramine maleate salt

Synonym(s):

(S)-γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine maleate salt

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1 g
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$154.00
$130.90
5 g
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$421.00

About This Item

Empirical Formula (Hill Notation):
C16H19ClN2 · C4H4O4
CAS Number:
2438-32-6
Molecular Weight:
390.86
NACRES:
NA.77
PubChem Substance ID:
24278317
UNSPSC Code:
12352116
EC Number:
219-450-6
MDL number:
MFCD00079046
Form:
powder

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form

powder

Quality Segment

200

originator

Bayer

SMILES string

[H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CC[C@@H](c1ccc(Cl)cc1)c2ccccn2

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1

InChI key

DBAKFASWICGISY-DASCVMRKSA-N

Gene Information

human ... HRH1(3269)

General description

Chlorpheniramine maleate is a cationic amphiphilic anti-histamine agent, which is composed of a hydrophobic ring structure and a hydrophilic side chain with a charged cationic amino group.[1]

Application

S-(+)-Chlorpheniramine maleate salt has been used to study the anticholinergic effect of Achillea millefolium and Portulaca olerace on muscarinic receptors of guinea pig tracheal smooth muscle.[2]

Biochem/physiol Actions

H1 histamine receptor antagonist; active isomer.
Chlorpheniramine maleate is clinically used as a topical ointment to treat skin disorders such as sunburn, urticaria, angioedema, pruritus and insect bites.[1]

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
C30251123000PHR1016
S-(+)-Chlorpheniramine maleate salt

Sigma-Aldrich

C4915

S-(+)-Chlorpheniramine maleate salt

(±)-Chlorpheniramine maleate salt ≥99% (perchloric acid titration)

Sigma-Aldrich

C3025

(±)-Chlorpheniramine maleate salt

Chlorpheniramine maleate United States Pharmacopeia (USP) Reference Standard

USP

1123000

Chlorpheniramine maleate

Chlorpheniramine Maleate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1016

Chlorpheniramine Maleate

form

powder

form

powder

form

-

form

-

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

300

originator

Bayer

originator

Bayer

originator

-

originator

-

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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