C5813
Complement factor H from human plasma
1 mg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE)
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| Size/SKU | Availability | Price |
|---|---|---|
0.1 mg | Estimated to ship onSeptember 30, 2026fromSAINT LOUIS | $726.00 |
About This Item
Form:
liquid
Assay:
≥90% (SDS-PAGE)
Biological source:
human plasma
Application
Complement factor H (CFH) is a plasma regulator of the complement protein C3b in the alternative pathway of the complement system. Research has shown that binding of CFH is important for pathogenesis of group A streptococcus (GAS), and inhibition of this binding may be an effective management of GAS infections.
Biochem/physiol Actions
C3b-binding protein which regulates the formation and function of complement C3 and C5 convertases.
Complement factor H plays an essential role in the homeostasis of the complement system and in preventing collateral damage to bystander cells and tissues by complement activation.
Other Notes
View more information on the complement pathway at www.sigma-aldrich.com/enzymeexplorer
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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This Item | |||
|---|---|---|---|
| description 1 mg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE) | description affinity isolated antibody, buffered aqueous solution | description for serum, plasma and cell culture supernatants | description - |
| assay ≥90% (SDS-PAGE) | assay - | assay - | assay - |
| technique(s) activity assay: suitable | technique(s) immunohistochemistry: suitable, western blot: suitable, indirect ELISA: suitable | technique(s) ELISA: suitable | technique(s) western blot: 1:500 - 1:2000 |
| biological source human plasma | biological source goat | biological source - | biological source rabbit |
| concentration 1 mg/mL in PBS, pH 7.2 | concentration - | concentration - | concentration 0.37 mg/mL |
| form liquid | form buffered aqueous solution | form - | form liquid |
| Gene Information human ... CFH(3075) | Gene Information human ... CFH(3075) | Gene Information human ... CFH(3075) | Gene Information human ... CFH(3075) |
Storage Class
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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