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(+/-)-Cloprostenol sodium salt hydrate

Name: (+/-)-Cloprostenol sodium salt hydrate
Brand: SIGMA
Price: 103 USD
Availability: InStock

≥98% (HPLC), powder

Synonym(s):

(+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate

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Size/SKU	Availability	Price
1 mg	Check Cart for Availability	$103.00
5 mg	Check Cart for Availability	$410.00

About This Item

Empirical Formula (Hill Notation):

C₂₂H₂₈ClNaO₆ · xH₂O

CAS Number:

55028-72-3

Molecular Weight:

446.90 (anhydrous basis)

MDL number:

MFCD11045985

UNSPSC Code:

12352200

PubChem Substance ID:

24724446

EC Number:

259-439-3

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

light brown

mp

68-70 °C

solubility

H₂O: >10 mg/mL

storage temp.

−20°C

SMILES string

[Na+].[H]O[H].O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]2[C@H](O)C[C@H](O)[C@@H]2C\C=C/CCCC([O-])=O

InChI

1S/C22H29ClO6.Na.H2O/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);;1H2/q;+1;/p-1/b3-1-,11-10+;;/t16-,18-,19-,20+,21-;;/m1../s1

InChI key

ZEQHRVULQBYULU-LPFHDDPUSA-M

Description

General description

Cloprostenol is a synthetic analogue of prostaglandin F2α (PGF). Cloprostenol contributes to the induction of estrus in animals and has uterotonic activity. Cloprostenol induces abortion in animals.

Application

(+/-)-Cloprostenol sodium salt hydrate has been used in studying its influence in oestrus synchronisation and uterine development in mice.

Biochem/physiol Actions

Cloprostenol is a potent FP prostanoid receptor agonist.

Cloprostenol is a potent FP prostanoid receptor agonist. It is 2- to 3-fold more potent than fluprostenol but less selective. Cloprostenol is similar in potency to PGF_2α at EP and TP prostanoid receptors. It is used for the treatment of infertility in sows and gilts.

Features and Benefits

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Show Differences

1 of 1

This Item	1140666	T4580	F8682
Sigma-Aldrich C6116 (+/-)-Cloprostenol sodium salt hydrate	USP 1140666 Cloprostenol sodium	Sigma-Aldrich T4580 Tiludronate disodium salt hydrate	Sigma-Aldrich F8682 Fosmidomycin sodium salt hydrate
description ≥98% (HPLC), powder	description United States Pharmacopeia (USP) Reference Standard	description ≥98% (HPLC)	description ≥95% (NMR)
form powder	form -	form powder	form powder
assay ≥98% (HPLC)	assay -	assay ≥98% (HPLC)	assay ≥95% (NMR)
Quality Level 100	Quality Level -	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. -	storage temp. −20°C
solubility H₂O: >10 mg/mL	solubility -	solubility H₂O: >10 mg/mL, clear	solubility H₂O: 20 mg/mL, clear
storage condition desiccated	storage condition -	storage condition desiccated	storage condition desiccated

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H315,H319,H335,H361

pcodes

P201 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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