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Chlorhexidine diacetate salt hydrate

Name: Chlorhexidine diacetate salt hydrate
Brand: SIGMA
Price: 268 USD
Availability: InStock

bis(biguanide) antimicrobial

Synonym(s):

1,6-Bis(N⁵-[p-chlorophenyl]-N¹-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)

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Size/SKU	Availability	Price
25 g	Available to ship TODAYfromMILWAUKEE	$268.00
100 g	Available to ship TODAYfromMILWAUKEE	$798.00

About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₀Cl₂N₁₀ · 2C₂H₄O₂ · xH₂O

CAS Number:

206986-79-0

Molecular Weight:

625.55 (anhydrous basis)

NACRES:

NA.85

PubChem Substance ID:

24892838

UNSPSC Code:

51102829

EC Number:

200-302-4

MDL number:

MFCD00012532

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Properties

Quality Segment

200

form

powder

CMC

0.01% (25°C)(w/v)

solubility

ethanol: 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell membrane | interferes

storage temp.

room temp

SMILES string

ClC1=CC=C(NC(NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N)=N)C=C1.OC(C)=O.OC(C)=O

InChI

1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)

InChI key

WDRFFJWBUDTUCA-UHFFFAOYSA-N

Description

Application

Used to study mechanism of membrane dysruption by bis(biguanide) molecules.

Biochem/physiol Actions

Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective against both Gram-positive and Gram-negative bacteria. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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This Item	C9394	PHR1294	C8527
Sigma-Aldrich C6143 Chlorhexidine diacetate salt hydrate	Sigma-Aldrich C9394 Chlorhexidine digluconate solution	Supelco PHR1294 Chlorhexidine digluconate	Sigma-Aldrich C8527 Chlorhexidine dihydrochloride
description bis(biguanide) antimicrobial	description 20% in H₂O	description Pharmaceutical Secondary Standard; Certified Reference Material	description ≥98%
mode of action cell membrane \| interferes	mode of action cell membrane \| interferes	mode of action -	mode of action -
antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria	antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria	antibiotic activity spectrum -	antibiotic activity spectrum -
Quality Level 200	Quality Level 200	Quality Level 300	Quality Level 100
form powder	form liquid	form -	form powder
solubility ethanol: 50 mg/mL	solubility water: soluble 50 % (w/v)	solubility -	solubility -
storage temp. room temp	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H302,H315,H319,H371,H410

pcodes

P260 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P311

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2

target_organs

Liver,Teeth

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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