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C7927

Cecropin P1 Porcine

≥95% (HPLC), powder

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Size/SKUAvailabilityPrice
0.1 mg

Available to ship TODAYfromMILWAUKEE

$276.00
$234.60
0.5 mg

Available to ship TODAYfromMILWAUKEE

$982.00
$834.70

About This Item

Empirical Formula (Hill Notation):
C147H253N45O43
CAS Number:
Molecular Weight:
3338.86
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:

$234.60

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Quality Segment

assay

≥95% (HPLC)

form

powder

antibiotic activity spectrum

fungi

mode of action

cell membrane | interferes

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)CO)C(C)O)C(C)CC)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C147H253N45O43/c1-18-75(9)113(140(229)167-81(15)120(209)188-114(76(10)19-2)141(230)168-82(16)121(210)189-115(77(11)20-3)142(231)178-94(47-50-106(154)198)123(212)164-66-108(200)163-68-110(202)192-60-36-46-105(192)139(228)179-97(145(234)235)45-35-59-161-147(158)159)187-109(201)67-165-124(213)95(48-51-111(203)204)176-138(227)104(72-196)186-143(232)116(78(12)21-4)190-130(219)93(44-34-58-160-146(156)157)174-127(216)90(41-26-31-55-150)172-125(214)88(39-24-29-53-148)170-118(207)79(13)166-136(225)102(70-194)184-135(224)101(64-107(155)199)183-129(218)96(49-52-112(205)206)177-132(221)98(61-73(5)6)181-128(217)91(42-27-32-56-151)173-126(215)89(40-25-30-54-149)171-119(208)80(14)169-144(233)117(83(17)197)191-131(220)92(43-28-33-57-152)175-137(226)103(71-195)185-133(222)99(62-74(7)8)182-134(223)100(180-122(211)86(153)69-193)63-84-65-162-87-38-23-22-37-85(84)87/h22-23,37-38,65,73-83,86,88-105,113-117,162,193-197H,18-21,24-36,39-64,66-72,148-153H2,1-17H3,(H2,154,198)(H2,155,199)(H,163,200)(H,164,212)(H,165,213)(H,166,225)(H,167,229)(H,168,230)(H,169,233)(H,170,207)(H,171,208)(H,172,214)(H,173,215)(H,174,216)(H,175,226)(H,176,227)(H,177,221)(H,178,231)(H,179,228)(H,180,211)(H,181,217)(H,182,223)(H,183,218)(H,184,224)(H,185,222)(H,186,232)(H,187,201)(H,188,209)(H,189,210)(H,190,219)(H,191,220)(H,203,204)(H,205,206)(H,234,235)(H4,156,157,160)(H4,158,159,161)

InChI key

PRIVBYDFWSFUFP-UHFFFAOYSA-N

General description

Cecropin P1 is found in Ascaris suum, which is a parasite that lives in porcine intestine.

Application

Cecropin P1 Porcine has been used to study its antimicrobial activity against Escherichia coli.

Biochem/physiol Actions

Antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.
Cecropin P1 can inhibit the growth of enterotoxigenic Escherichia coli in porcine. It also can inhibit the growth of human fungal pathogen Candida albicans. Cecropin P1 also blocks the release of viral particles and impairs virus-induced apoptosis. Cecropins are cationic anti-microbial peptides (AMPs). It can inactivate microorganisms by forming an α-helical chain which punctures the cell membrane. Cecropins may be used in food preservation as it is non-cytotoxic to mammalian cells.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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This Item
C6830516360N8630
description

≥95% (HPLC), powder

description

≥97% (HPLC), powder

description

Catalyzes the hydrolysis of aminoacyl-proline to an amino acid and proline. Inhibitors include aliphatic alcohols, pepstatin A, and pH 6.0.

description

lyophilized powder, ≥200 units/mg protein (E1%/280, 3′-5′-Phosphodiesterase)

mode of action

cell membrane | interferes

mode of action

cell membrane | interferes

mode of action

-

mode of action

-

antibiotic activity spectrum

fungi

antibiotic activity spectrum

fungi, viruses

antibiotic activity spectrum

-

antibiotic activity spectrum

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

assay

≥95% (HPLC)

assay

≥97% (HPLC)

assay

-

assay

-

form

powder

form

powder

form

lyophilized

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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