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C7938

2-Chloro-N6-cyclopentyladenosine

adenosine receptor agonist

Synonym(s):

CCPA

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Size/SKUAvailabilityPrice
10 mg
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$279.00

About This Item

Empirical Formula (Hill Notation):
C15H20ClN5O4
CAS Number:
37739-05-2
Molecular Weight:
369.80
NACRES:
NA.51
PubChem Substance ID:
24892583
UNSPSC Code:
41106305
MDL number:
MFCD00078574
Assay:
≥98% (TLC)
Form:
powder
Solubility:
methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
Storage temp.:
2-8°C

$279.00

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Quality Segment

200

assay

≥98% (TLC)

form

powder

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC4CCCC4)nc(Cl)nc23

InChI

1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1

InChI key

XSMYYYQVWPZWIZ-IDTAVKCVSA-N

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

Application

2-Chloro-N6-cyclopentyladenosine (CCPA) may be used as an A1 adenosine receptor agonist with high selectivity. CCPA is often used with other adenosine receptor agonists and antagonist to resolve A(1), A(2A) and A(3) receptor functions. These include DPCPX (A(1) receptor antagonist), 4-(2-[7-amino-2-(2-furyl)[1,2,4]triazolo[2,3-α][1,3,5]triazin-5-ylamino]ethyl)phenol (A(2A) receptor antagonist), and 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride (A(2A) receptor agonist), and Cl-IB-MECA, (A(3)) receptor agonist).

Biochem/physiol Actions

A1 adenosine receptor agonist with high selectivity: reportedly 10,000-fold for A1 over A2 receptors.

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This Item
C8031M6018L5139
2-Chloro-N6-cyclopentyladenosine adenosine receptor agonist

Sigma-Aldrich

C7938

2-Chloro-N6-cyclopentyladenosine

N6-Cyclopentyladenosine solid

Sigma-Aldrich

C8031

N6-Cyclopentyladenosine

4-Methylumbelliferyl β-D-cellobioside glucanase substrate

Sigma-Aldrich

M6018

4-Methylumbelliferyl β-D-cellobioside

Lycorine hydrochloride ≥98% (TLC), powder

Sigma-Aldrich

L5139

Lycorine hydrochloride

description

adenosine receptor agonist

description

solid

description

glucanase substrate

description

≥98% (TLC), powder

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

assay

≥98% (TLC)

assay

-

assay

≥98.00% (TLC)

assay

≥98% (TLC)

form

powder

form

solid

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 1.7 mg/mL, 0.1 M HCl: 12 mg/mL, DMSO: 23 mg/mL

solubility

water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

solubility

ethanol: 10 mg/mL, clear, colorless to very faintly yellow

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA3(140)
mouse ... Adora1(11539)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

Gene Information

-

Gene Information

-

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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