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C8115

Coronatine

from Pseudomonas syringae pv Glycinea, >95% (HPLC)

Synonym(s):

COR, Cyclopropanecarboxylic acid,2-ethyl-1-[[(6-ethyl-2,3,3a,6,7a-hexahydro-1-oxo-1H-inden-4-yl)carbonyl] amino]

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1 MG

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About This Item

Empirical Formula (Hill Notation):
C18H25NO4
Molecular Weight:
319.40
NACRES:
NA.85
PubChem Substance ID:
329775160
UNSPSC Code:
51102829
MDL number:
MFCD06798335

Key Documents

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InChI

1S/C18H25NO4/c1-3-10-7-13-12(5-6-15(13)20)14(8-10)16(21)19-18(17(22)23)9-11(18)4-2/h8,10-13H,3-7,9H2,1-2H3,(H,19,21)(H,22,23)

SMILES string

CCC1CC2C(CCC2=O)C(=C1)C(=O)NC3(CC3CC)C(O)=O

InChI key

FMGBNISRFNDECK-UHFFFAOYSA-N

biological source

Pseudomonas syringae pv Glycinea

assay

>95% (HPLC)

form

powder

solubility

H2O: soluble 0.2 mg/mL, DMSO: soluble 20 mg/mL, methanol: soluble 20 mg/mL

mode of action

enzyme | interferes

storage temp.

−20°C

Quality Level

200

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Coronatine from Pseudomonas syringae pv Glycinea, >95% (HPLC)

Sigma-Aldrich

C8115

Coronatine

AZD1283 ≥98% (HPLC)

Sigma-Aldrich

SML2080

AZD1283

Ex26 ≥98% (HPLC)

Sigma-Aldrich

SML1680

Ex26

DCPIB ≥98% (HPLC)

Sigma-Aldrich

SML2692

DCPIB

mode of action

enzyme | interferes

mode of action

-

mode of action

-

mode of action

-

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

-

assay

>95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

solubility

H2O: soluble 0.2 mg/mL, methanol: soluble 20 mg/mL, DMSO: soluble 20 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 25 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

biological source

Pseudomonas syringae pv Glycinea

biological source

-

biological source

-

biological source

-

Application

Coronatine is a polyketide phytotoxin produced by several members of the Pseudomonas syringae group of pathovars such as atropurpurea, glycinea, maculicola,morsprunorum and tomato. Coronatine was used to study the regulatory genes: corP, corS and corR.[1] It was used to study the stimulation of ethylene synthesis in Nicotiana tabacum leaves.[2]

Biochem/physiol Actions

Coronatine is a polyketide phytotoxin produced by several members of the Pseudomonas syringae group of pathovars. It consists of two distinct structural components that function as biosynthetic intermediates: coronafacic acid (CFA) and coronamic acid (CMA). It is known to induce hypertrophy and chlorosis, inhibit root elongation, and stimulate ethylene production.
Coronatine is a polyketide phytotoxin produced by several members of the Pseudomonas syringae group of pathovars. It is known to induce hypertrophy and chlorosis, inhibit root elongation, and stimulate ethylene production.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000398551
0000398551
0000375258
0000352512
0000352512

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Minoru Ueda et al.
ACS central science, 3(5), 462-472 (2017-06-03)
Coronatine (
C Dutheil et al.
Scientific reports, 10(1), 4838-4838 (2020-03-18)
Climate model projections generally indicate fewer but more intense tropical cyclones (TCs) in response to increasing anthropogenic emissions. However these simulations suffer from long-standing biases in their Sea Surface Temperature (SST). While most studies investigating future changes in TC activity
Jia Xu et al.
American journal of cancer research, 6(11), 2700-2712 (2016-12-03)
The Delta-like 1 homolog (DLK1) gene is a paternal imprinting gene located on human chromosome 14q32, a site associated with frequent chromosomal mutations in GIST. The expression level of DLK1 is closely associated with the outcome of tumours. However, no
J S Kenyon et al.
Plant physiology, 100(1), 219-224 (1992-09-01)
Coronatine is a chlorosis-inducing toxin produced by the plant pathogen Pseudomonas syringae pv atropurpurea. This bacterium is the causal agent of chocolate spot disease, in which brown lesions with chlorotic margins develop on the leaves of Lolium multiflorum Lam. Among
Alejandro Peñaloza-Vázquez et al.
Microbiology (Reading, England), 146 ( Pt 10), 2447-2456 (2000-10-06)
In P. syringae, the co-ordinated regulation of different systems required for pathogenicity and virulence seems logical but has not been established. This question was addressed in the present study by analysing production of the phytotoxin coronatine (COR) in defined hrp/hrc
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Product Information Sheet - C8115

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