Skip to Content
MilliporeSigma

Skip To

C9137

Cordycepin 5′-triphosphate sodium salt

≥95%

Synonym(s):

3′-dATP, 3′-deoxy-ATP, 3′-Deoxyadenosine 5′-triphosphate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
1 mg
Check Cart for Availability
$225.00
5 mg
Check Cart for Availability
$876.00

About This Item

Empirical Formula (Hill Notation):
C10H16N5O12P3
CAS Number:
Molecular Weight:
491.18
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
eCl@ss:
32119108
Assay:
≥95%
Form:
powder

$225.00


Check Cart for Availability

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥95%

form

powder

mol wt

491.18  g/mol

storage temp.

−20°C

SMILES string

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)CC3O

InChI

1S/C10H16N5O12P3.Na.H/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(16)1-5(25-10)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-6,10,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);;

InChI key

FRGBONDYLMUOMH-UHFFFAOYSA-N

General description

Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin.

Application

Cordycepin 5′-triphosphate sodium salt has been used:
  • as a transcriptional inhibitor in RNA decay assay
  • to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
  • as a positive control in in vitro assays for polymerase inhibition
  • as a precursor to produce cordycepin monophosphate

Biochem/physiol Actions

Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis.
Cordycepin 5′-triphosphate is incorporated into nucleic acid by poly(A) polymerase. Because it lacks a 3′-hydroxyl group chain production it can be used for 3′-end labeling of RNA.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
C3394PHL82505A9187
description

≥95%

description

from Cordyceps militaris

description

phyproof® Reference Substance

description

≥95%, bacterial

form

powder

form

powder

form

-

form

powder

assay

≥95%

assay

-

assay

≥95.0% (HPLC)

assay

≥95%

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

mol wt

491.18  g/mol

mol wt

-

mol wt

-

mol wt

-


Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

PPE (personal protective equipment)

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters