C9848
抗钙结合蛋白D-28K单克隆抗体 小鼠抗
增強驗證
clone CB-955, ascites fluid
同義詞:
钙结合蛋白抗体, 钙结合蛋白抗体 - 小鼠钙结合蛋白D-28K单克隆抗体
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biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
CB-955, monoclonal
mol wt
antigen 28 kDa
contains
15 mM sodium azide
species reactivity
mouse, human, guinea pig, canine, sheep, rat, pig, rabbit, feline, bovine, goat
enhanced validation
independent
Learn more about Antibody Enhanced Validation
concentration
15-55 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:3,000 using rat cerebellum sections, indirect ELISA: suitable, western blot: 1:3,000 using MDBK cell extract
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CALB1(793)
mouse ... Calb1(12307)
rat ... Calb1(83839)
General description
钙结合蛋白D-28K单克隆抗体（小鼠IgG1同种型）来源于CB-955杂交瘤，该杂交瘤由小鼠骨髓瘤细胞和用纯化的牛肾钙结合蛋白D-28K免疫的BALB/c小鼠的脾细胞融合产生。使用小鼠单克隆抗体分型试剂（产品号ISO2）进行双向免疫扩散实验，从而确定同种型。
钙结合蛋白D-28K和钙调蛋白、S-100、小白蛋白、肌钙蛋白C等蛋白质同属于低分子量钙结合蛋白（CaBP）家族。这些CaBP具有同源的一级结构，其含有EF-手型的多肽折叠结构以接受Ca2+。钙结合蛋白是一种新颖的神经解剖学标记物。尽管钙结合蛋白D-28K的组织分布广泛，但它表现出细胞类型特异性表达模式。因此，它已被免疫细胞化学定位于许多CNS结构的指定细胞中，作为细胞内钙缓冲剂或作用于钙的膜内转运。它主要存在于中枢和外周神经系统神经元的亚群中，以及参与Ca2+ 转运的某些上皮细胞中，如肾的远端肾小管细胞和皮质集合小管，以及肠神经内分泌细胞。与钙结合蛋白D-28K发生特异性反应的单克隆抗体有助于钙结合蛋白在不同组织和细胞群中的定位。
Immunogen
Application
Biochem/physiol Actions
Physical form
Preparation Note
Disclaimer
1 of 1
本產品 | |||
|---|---|---|---|
| species reactivity mouse, human, guinea pig, canine, sheep, rat, pig, rabbit, feline, bovine, goat | species reactivity mouse, human, rat | species reactivity fish, frog, rabbit, canine, feline, bovine, pig, human, goat, rat | species reactivity feline, human, pig |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| Gene Information human ... CALB1(793) | Gene Information human ... CALB1(793) | Gene Information human ... PVALB(5816) | Gene Information human ... LAMA1(284217), LAMA2(3908), LAMB1(3912), LAMB2(3913) |
| antibody form ascites fluid | antibody form purified immunoglobulin | antibody form ascites fluid | antibody form purified from hybridoma cell culture |
| clone CB-955, monoclonal | clone CB-955, monoclonal | clone PARV-19, monoclonal | clone LAM-89, monoclonal |
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存儲類別/等級
10 - Combustible liquids
wgk
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