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D0776

2′-Deoxycytidine hydrochloride

BioReagent, suitable for cell culture

Synonym(s):

1-(2-Deoxy-β-D-ribofuranosyl)cytosine hydrochloride, Cytosine deoxyriboside hydrochloride

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250 MG

$47.90

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$137.00

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About This Item

Empirical Formula (Hill Notation):
C9H13N3O4 · HCl
CAS Number:
3992-42-5
Molecular Weight:
263.68
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24893295
EC Number:
223-639-9
Beilstein/REAXYS Number:
3576124
MDL number:
MFCD00012840
Assay:
≥99% (HPLC)
Form:
powder

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biological source

synthetic

Quality Level

300

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

water: 50 mg/mL, clear, colorless

SMILES string

Cl[H].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2

InChI

1S/C9H13N3O4.ClH/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H/t5-,6+,8+;/m0./s1

InChI key

LTKCXZGFJFAPLY-OERIEOFYSA-N

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1 of 4

This Item
D8006C6645D3897
2′-Deoxycytidine hydrochloride BioReagent, suitable for cell culture

Sigma-Aldrich

D0776

2′-Deoxycytidine hydrochloride

2′-Deoxycytidine hydrochloride analytical standard, ≥99%

Supelco

D8006

2′-Deoxycytidine hydrochloride

Cytosine β-D-arabinofuranoside hydrochloride crystalline

C6645

Cytosine β-D-arabinofuranoside hydrochloride

2′-Deoxycytidine ≥99% (HPLC)

D3897

2′-Deoxycytidine

assay

≥99% (HPLC)

assay

≥99%

assay

≥99% (HPLC)

assay

≥99% (HPLC)

solubility

water: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

-

form

crystalline

form

powder

biological source

synthetic

biological source

-

biological source

synthetic (inorganic)

biological source

synthetic (organic)

product line

BioReagent

product line

-

product line

-

product line

-

Application

2′-Deoxycytidine hydrochloride has been used:
  • as a deoxyribonucleoside component in the basal medium to study its effects on Bacillus mojavensis′s anaerobic growth
  • in the infectivity assay of monocyte-derived macrophages by human immunodeficiency virus 1 (HIV-1)
  • in nucleoside supplementation for the synchronization of human retinal pigment epithelial-1 (RPE-1) cells in G1 phase

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000493569
0000493569
0000491948
0000491948
0000380042

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Fuxia Li et al.
American journal of cancer research, 10(3), 908-924 (2020-04-09)
Epithelial ovarian cancer is characterized by universal TP53 mutations, which result in G1/S checkpoint deficiencies. Therefore, it is hypothesized that the abrogation of the G2/M checkpoint with Wee1 inhibitor might preferentially sensitize TP53-defective ovarian cancer cells. Given the extremely high
Md Maminur Rahman et al.
The Journal of biological chemistry, 295(51), 17460-17475 (2021-01-18)
Homologous recombination (HR) repairs DNA double-strand breaks using intact homologous sequences as template DNA. Broken DNA and intact homologous sequences form joint molecules (JMs), including Holliday junctions (HJs), as HR intermediates. HJs are resolved to form crossover and noncrossover products.
null
Aiman A Haqqani et al.
Virology journal, 12, 184-184 (2015-11-13)
Template switching between two distinct HIV-1 RNA genomes during reverse transcription gives rise to recombinant viruses that greatly expand the genetic diversity of HIV-1 and have adverse implications for drug resistance, immune escape, and vaccine design. Virions with two distinct
Harry E Taylor et al.
Cell reports, 31(12), 107810-107810 (2020-06-25)
Cellular metabolism governs the susceptibility of CD4 T cells to HIV-1 infection. Multiple early post-fusion steps of HIV-1 replication are restricted in resting peripheral blood CD4 T cells; however, molecular mechanisms that underlie metabolic control of these steps remain undefined. Here, we
View All Related Papers

Global Trade Item Number

SKUGTIN
D0776-1G04061833558058
D0776-250MG04061833558065

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