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D4422

Docusate sodium salt

BioXtra, ≥99%

Synonym(s):

AOT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Sodium bis(2-ethylhexyl) sulfosuccinate, Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt, Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt, Dioctyl sulfosuccinate sodium salt

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Pack SizeSKUAvailabilityPrice
50 g

Available to ship TODAYfromMILWAUKEE

$142.00
100 g

Available to ship TODAYfromMILWAUKEE

$225.00
500 g

Estimated to ship onApril 24, 2026fromMILWAUKEE

$847.00

About This Item

Empirical Formula (Hill Notation):
C20H37NaO7S
CAS Number:
Molecular Weight:
444.56
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
209-406-4
Beilstein/REAXYS Number:
4117588
MDL number:

$142.00


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description

anionic

product line

BioXtra

assay

≥99%

form

sheet

mol wt

444.56 g/mol

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

solubility

passes test (per USP)

cation traces

Al: ≤0.001%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.01%, Mg: ≤0.0005%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

[Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S([O-])(=O)=O

InChI

1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1

InChI key

APSBXTVYXVQYAB-UHFFFAOYSA-M

General description

Docusate sodium salt is an anionic surfactant.

Application

Forms reverse micelles in hydrocarbon solvents; Suitable for the solubilization of the major myelin transmembrane proteolipid
Docusate sodium salt has been used in a study to assess chromatography approaches for early screening of the phospholipidosis-inducing potential of pharmaceuticals. [1] It has also been used in a study to investigate different formulations for drug delivery through the nail plate.

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This Item
86139D1685PHR2728
assay

≥99%

assay

≥99.0% (TLC)

assay

99.0-100.5% anhydrous basis

assay

-

form

sheet

form

sheet

form

solid

form

solid

cation traces

Al: ≤0.001%, Cu: ≤0.0005%, K: ≤0.01%, Pb: ≤0.001%, Ca: ≤0.001%, Mg: ≤0.0005%, Fe: ≤0.0005%, Zn: ≤0.0005%

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤100 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

-

cation traces

-

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

insoluble matter, passes filter test

impurities

-

impurities

-

description

anionic

description

anionic

description

anionic

description

Pharmaceutical Secondary Standard; Certified Reference Material

mol wt

444.56 g/mol

mol wt

444.56 g/mol

mol wt

444.56 g/mol

mol wt

-


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Investigation of different formulations for drug delivery through the nail plate
Vejnovic, I., et al.
International Journal of Pharmaceutics, 386, 10-10 (2010)
Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres
Kokai, L., et al.
J. Controlled Release, 141, 9-9 (2010)
Zhengjin Jiang et al.
Journal of pharmaceutical and biomedical analysis, 61, 184-190 (2011-12-28)
Drug-induced phospholipidosis (PLD) is an excessive accumulation of polar phospholipids within cells as a result of medical treatment. Even though a direct link between in vitro drug-induced PLD and toxicity in humans has not yet been firmly established, the development



Global Trade Item Number

SKUGTIN
D4422-50G04061833564417
D4422-100G04061833564400
D4422-500G04061835543953

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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